{"id":"W2055950362","doi":"10.1002/mrd.20203","title":"Fundamental significance of specific phosphodiesterases in the control of spontaneous meiotic resumption in porcine oocytes","year":2004,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"IBMX; Germinal vesicle; Forskolin; Phosphodiesterase; Meiosis; Rolipram; Oocyte; Biology; Andrology; Oogenesis; Phosphodiesterase inhibitor; Adenylyl cyclase; Endocrinology; Stimulation; Internal medicine; Embryo; Cell biology; Medicine; Genetics; Enzyme; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003481163,0.0001033247,0.0001412849,0.0000800377,0.0000298589,0.000007858983,0.0000548668,0.00005041601,0.000005697057],"category_scores_gemma":[0.00003571837,0.00008353873,0.00002615908,0.0001215082,0.00008103361,0.000005828606,0.00001845815,0.00005137744,8.466718e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003973594,"about_ca_system_score_gemma":0.00005929698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000366318,"about_ca_topic_score_gemma":0.00006006512,"domain_scores_codex":[0.9990356,0.0000623555,0.0003466493,0.0003032187,0.0001472264,0.00010493],"domain_scores_gemma":[0.9995975,0.000007179829,0.0001140047,0.0002168152,0.00004556287,0.00001886446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007125243,0.0002660583,0.009390935,0.00005253086,0.00002433113,0.00004211051,0.0009171534,0.003950755,0.9791915,0.0001956742,0.00002216902,0.005234209],"study_design_scores_gemma":[0.001760899,0.000167943,0.1610284,0.00005496691,0.000005296001,0.0001487945,0.0005218761,0.000006596828,0.8321524,0.0000789081,0.003949999,0.0001239248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945664,0.002077189,0.002589602,0.0002652062,0.0001092669,0.0003320979,0.000001944411,0.000003658848,0.00005457715],"genre_scores_gemma":[0.998799,0.0002152243,0.0007687185,0.00008769434,0.00002184576,0.00002162896,0.00004111664,0.000006812356,0.00003800268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1516374,"threshold_uncertainty_score":0.340661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01086919777494946,"score_gpt":0.2234330605833769,"score_spread":0.2125638628084275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}