{"id":"W2056011173","doi":"10.1074/jbc.m114.558668","title":"Targeting the Transient Receptor Potential Vanilloid Type 1 (TRPV1) Assembly Domain Attenuates Inflammation-induced Hypersensitivity","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"TRPV1; Transient receptor potential channel; Chemistry; Protein subunit; Biophysics; Cell biology; Capsaicin; Biochemistry; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002096147,0.0004842353,0.0007481146,0.0002764719,0.0002451046,0.0003819652,0.0004576871,0.0004444801,0.00138272],"category_scores_gemma":[0.0001911829,0.0001780035,0.0002801837,0.0001731448,0.0004608721,0.0004158849,0.0002274139,0.00171591,0.0002988444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003290435,"about_ca_system_score_gemma":0.0004398146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006626816,"about_ca_topic_score_gemma":0.00100827,"domain_scores_codex":[0.999742,0.00003506175,0.00002312976,0.00004590659,0.00005682597,0.00009708847],"domain_scores_gemma":[0.9998802,0.00001569217,0.00003103226,0.00001288932,0.00001634309,0.00004385006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002634929,0.0001186903,0.00003136729,0.00002932093,0.00000455694,0.00001624209,0.00001078775,0.00008010407,0.9983462,0.0001051426,0.00005466751,0.0009394397],"study_design_scores_gemma":[0.00007116335,0.001046163,0.001148194,0.000007796852,0.00002906689,0.00007950241,0.00003330642,0.001122829,0.9950445,0.00006553531,0.001345509,0.000006435363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921846,0.001342457,0.004554769,0.0003148014,0.0001375403,0.0000543807,0.0002528129,0.0002069727,0.0009516063],"genre_scores_gemma":[0.9930307,0.001057195,0.002666656,0.0001380542,0.00002773137,0.00006984764,0.0003978275,0.00004281844,0.002569193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00138272,"threshold_uncertainty_score":0.004625618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02643912915561081,"score_gpt":0.2449755369544242,"score_spread":0.2185364077988134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}