{"id":"W2056022475","doi":"10.1089/scd.2004.13.694","title":"Monitoring Early Differentiation Events in Human Embryonic Stem Cells by Massively Parallel Signature Sequencing and Expressed Sequence Tag Scan","year":2004,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Biology; Embryoid body; Embryonic stem cell; Gene; Cellular differentiation; Gene expression profiling; Gene expression; Genetics; Massive parallel sequencing; Induced pluripotent stem cell; Computational biology; Molecular biology; Cell biology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004713286,0.0002767546,0.0003812981,0.0005671603,0.0002046064,0.0004575283,0.0001979882,0.0002242286,0.0004076293],"category_scores_gemma":[0.0007028228,0.0001639649,0.0002157533,0.0006542272,0.0001977502,0.000191103,0.000260603,0.0003869645,0.0003398622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002355595,"about_ca_system_score_gemma":0.0002485112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004576328,"about_ca_topic_score_gemma":0.001199515,"domain_scores_codex":[0.9996816,0.00004139494,0.00002925063,0.00008627528,0.0001382711,0.00002328112],"domain_scores_gemma":[0.9996841,0.00009503366,0.00007074975,0.00003940536,0.00008200393,0.00002869293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001414104,0.00001914223,0.002390475,0.00003478921,0.000009245886,0.00004400491,0.00003166675,0.0004150513,0.990274,0.00009969809,0.00004703331,0.00649352],"study_design_scores_gemma":[0.0000153572,0.0001706497,0.03172377,0.000006014649,0.00003541159,0.000311454,0.00004484607,0.0082282,0.9578875,0.0002897014,0.001273249,0.00001391909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466527,0.0004901651,0.0483225,0.00006986678,0.00001417433,0.0001096402,0.00277107,0.0003104398,0.001259421],"genre_scores_gemma":[0.81476,0.0009073208,0.1730452,0.0001962964,0.00001960338,0.0002925164,0.007643037,0.000108414,0.003027532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005671603,"threshold_uncertainty_score":0.002492607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02085523579105848,"score_gpt":0.2487019729983335,"score_spread":0.227846737207275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}