{"id":"W2056040906","doi":"10.1186/1471-2466-14-178","title":"Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study","year":2014,"lang":"en","type":"article","venue":"BMC Pulmonary Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":174,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Medicine; COPD; Formoterol; Formoterol Fumarate; Placebo; Fixed-dose combination; Minimal clinically important difference; Internal medicine; Randomized controlled trial; Physical therapy; Asthma; Alternative medicine; Budesonide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001075357,0.0005527717,0.001450754,0.0005690221,0.0001986144,0.0000216064,0.0002575442,0.0001036239,0.00007919156],"category_scores_gemma":[0.0003983419,0.0003833903,0.0000520902,0.000576211,0.0008267938,0.0002668806,0.0002409801,0.000510511,0.000009541467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001896451,"about_ca_system_score_gemma":0.0001935827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000279087,"about_ca_topic_score_gemma":0.0001689773,"domain_scores_codex":[0.995557,0.0005689409,0.001028545,0.0008043833,0.001388249,0.0006528559],"domain_scores_gemma":[0.9968203,0.001108986,0.0004179601,0.0006438857,0.0003611174,0.0006477198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1390147,0.004963466,0.8507745,0.000769342,0.0003030407,0.00008256381,0.001404006,0.00004429261,0.0001244059,0.00001460617,0.00006484102,0.002440226],"study_design_scores_gemma":[0.274507,0.002062404,0.7136689,0.0009489658,0.0004410264,0.00003729571,0.001547041,0.006454206,0.00001356708,0.000010796,0.00005062002,0.0002581524],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905118,0.0003092182,0.00007913261,0.0002778941,0.00007729512,0.007889613,0.0001202956,0.00005214936,0.0006826352],"genre_scores_gemma":[0.9984241,0.00003988128,0.0003094475,0.00009964989,0.00006483546,0.000166546,0.0007271884,0.00006839646,0.0001000126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1371056,"threshold_uncertainty_score":0.9998618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02019549787640459,"score_gpt":0.2730075560991478,"score_spread":0.2528120582227432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}