{"id":"W2056087429","doi":"10.1016/j.cell.2015.02.051","title":"Transcription Gets to the Checkpoint","year":2015,"lang":"en","type":"letter","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Biology; Transcription (linguistics); G2-M DNA damage checkpoint; Transcription factor; Genetics; Computational biology; Cell biology; Cell cycle checkpoint; Gene; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003174716,0.0002163452,0.0001524302,0.00004867253,0.00005788535,0.00004479737,0.000596051,0.0005742035,0.00004996933],"category_scores_gemma":[0.00002526404,0.0001564298,0.000144435,0.00005217663,0.00004479466,0.000001074812,0.0001497679,0.0006454873,0.0009300523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003857347,"about_ca_system_score_gemma":0.0001508389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002654805,"about_ca_topic_score_gemma":0.00002378419,"domain_scores_codex":[0.9984555,0.0001260145,0.0001718942,0.0004557939,0.0003821157,0.0004087384],"domain_scores_gemma":[0.9989895,0.000006758586,0.00004851709,0.0007269375,0.0001329054,0.00009537669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001257749,0.00000913455,7.57e-7,0.00004555133,0.00001285785,0.00002920303,0.00003316836,0.00001154663,0.2825188,5.353429e-8,0.7170852,0.0002411365],"study_design_scores_gemma":[0.0001463074,0.0001107484,0.000007637881,0.00000863494,0.00001333949,0.000007088107,0.000008740863,0.000006647033,0.1970071,0.000009720898,0.8025112,0.0001628434],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.009990877,0.00496247,0.0008484963,0.9324459,0.001318525,0.001240503,0.0001633012,0.00003078415,0.04899917],"genre_scores_gemma":[0.01682177,0.0005946007,0.0002486887,0.6991307,0.01126206,0.0001864005,0.002740698,0.0001607487,0.2688544],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2333152,"threshold_uncertainty_score":0.9998478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02460687101431428,"score_gpt":0.2594495635310435,"score_spread":0.2348426925167292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}