{"id":"W2056093824","doi":"10.1038/ncomms5285","title":"A role for DNA polymerase θ in the timing of DNA replication","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Nautical Research Society","funders":"Centre National de la Recherche Scientifique; Groupement des Entreprises Françaises dans la lutte contre le Cancer; Ligue Contre le Cancer","keywords":"DNA replication; DNA polymerase; Replication timing; Origin recognition complex; Biology; Chromatin; Eukaryotic DNA replication; Control of chromosome duplication; DNA polymerase delta; Cell biology; DNA replication factor CDT1; Genetics; DNA; Gene; RNA; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001269659,0.0006072269,0.0006119795,0.0008003844,0.000918309,0.003985665,0.001414035,0.001678803,0.005009709],"category_scores_gemma":[0.003494075,0.000847678,0.0005238429,0.000510754,0.001555129,0.003950147,0.001039168,0.001613549,0.002102857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00135112,"about_ca_system_score_gemma":0.001236113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001325368,"about_ca_topic_score_gemma":0.001225158,"domain_scores_codex":[0.9993865,0.00008205931,0.00005632866,0.0002511152,0.0001159263,0.0001079687],"domain_scores_gemma":[0.9981184,0.0005975846,0.0003651231,0.0003247625,0.0002632441,0.0003309428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001918105,0.00006578047,0.00351439,0.0003760505,0.0000376064,0.0003845744,0.0002010737,0.002302689,0.9259847,0.03373899,0.001279798,0.0301961],"study_design_scores_gemma":[0.0002387225,0.0009858258,0.01937446,0.0002073596,0.00008363371,0.001450612,0.0006124784,0.01615496,0.8959943,0.02641506,0.03819177,0.0002908084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.688325,0.07562345,0.1805386,0.00612154,0.007080367,0.000167962,0.001218501,0.003390574,0.037534],"genre_scores_gemma":[0.9771246,0.006692725,0.01048625,0.0002855319,0.0003393329,0.0000355532,0.0002813476,0.0001543265,0.00460035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005009709,"threshold_uncertainty_score":0.01675916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552625791275592,"score_gpt":0.3014065613507297,"score_spread":0.2858803034379738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}