{"id":"W2056206189","doi":"10.1016/s1388-1981(00)00094-9","title":"Activation of phospholipase D by PKC and GTPγS in human neuroblastoma cells overexpressing MARCKS","year":2000,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council","keywords":"MARCKS; Protein kinase C; Phospholipase D; GTPgammaS; Phosphatidylethanol; Digitonin; PLD2; Staurosporine; Phosphorylation; Molecular biology; Cell biology; Biology; Myristoylation; Biochemistry; Chemistry; Signal transduction; G protein; Phospholipid; Phosphatidylcholine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000129678,0.0003037218,0.0003810564,0.0000874717,0.00006448017,0.00001951629,0.0002030663,0.0003118263,0.00002406031],"category_scores_gemma":[0.0000119203,0.0003029787,0.0001141021,0.0001489354,0.0004499102,0.00001372903,0.0001358066,0.0001665967,8.364649e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006077594,"about_ca_system_score_gemma":0.0000489497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008804927,"about_ca_topic_score_gemma":0.000002641591,"domain_scores_codex":[0.9984511,0.0001342993,0.0004175183,0.0005904234,0.0001060162,0.0003006262],"domain_scores_gemma":[0.999271,0.00002529492,0.0002154387,0.0003415407,0.0000498396,0.00009684642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002252925,0.0002716933,0.00003918719,0.0001259304,0.00003834772,0.000001499871,0.000103562,0.000006463339,0.9977942,0.00002982936,0.0002195394,0.001144453],"study_design_scores_gemma":[0.001002869,0.0006655115,0.0003538806,0.00005016146,0.00003557574,0.000004215383,0.00004415846,0.00002420763,0.9963036,0.0001502925,0.001070303,0.0002952477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977138,0.0007625988,0.00007357811,0.00009015154,0.00004099239,0.0001925519,0.00006643757,0.00001006227,0.001049847],"genre_scores_gemma":[0.9981833,0.0008956503,0.0001387321,0.0002446406,0.00004935857,0.00001160344,0.0002655688,0.00003352825,0.000177628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001490625,"threshold_uncertainty_score":0.9999422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003861635729319818,"score_gpt":0.218997191550896,"score_spread":0.2151355558215762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}