{"id":"W2056351891","doi":"10.1097/01.lab.0000082383.40635.fe","title":"Altered Expression of Angiopoietins During Blood-Brain Barrier Breakdown and Angiogenesis","year":2003,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; University Health Network","funders":"Ontario Neurotrauma Foundation; Heart and Stroke Foundation of Canada","keywords":"Angiopoietin; Angiogenesis; Choroid plexus; Blood–brain barrier; Angiopoietin receptor; Autocrine signalling; Biology; Endothelial stem cell; Endocrinology; Internal medicine; Paracrine signalling; Tight junction; Fibronectin; Receptor; Vascular endothelial growth factor; Cell biology; Central nervous system; Medicine; Cancer research; Extracellular matrix; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002687607,0.0001449436,0.0002486946,0.0004699341,0.0002438905,0.0004853214,0.0002642066,0.0003293941,0.0008867406],"category_scores_gemma":[0.0004708125,0.0001703613,0.0001869504,0.0003368451,0.0004911525,0.0004701985,0.0002006868,0.0007058145,0.000210973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000532601,"about_ca_system_score_gemma":0.0002489167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007727539,"about_ca_topic_score_gemma":0.0004935257,"domain_scores_codex":[0.9998074,0.00004535302,0.00001512454,0.00002889576,0.00002970995,0.00007348727],"domain_scores_gemma":[0.999756,0.0000663301,0.00006436099,0.00002341144,0.00002926134,0.00006049576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002251912,0.00007374315,0.0008144988,0.00004369121,0.00001031602,0.000498961,0.00008171253,0.00006605687,0.9930461,0.0007830407,0.00008330605,0.00224672],"study_design_scores_gemma":[0.00006395977,0.0005830775,0.0239305,0.000008312706,0.00003989501,0.001499996,0.0001970859,0.000902124,0.9700571,0.0004648367,0.002244764,0.000008302018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945204,0.002281861,0.001761074,0.00008725101,0.00002645058,0.00001955665,0.0001453056,0.00002969121,0.001128537],"genre_scores_gemma":[0.996795,0.0006996776,0.0009530924,0.00003177045,0.00001778071,0.00004254322,0.0002018222,0.000008083063,0.001250123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008867406,"threshold_uncertainty_score":0.003864288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006932541622924349,"score_gpt":0.2177385442621587,"score_spread":0.2108060026392344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}