{"id":"W2056351891","doi":"10.1097/01.lab.0000082383.40635.fe","title":"Altered Expression of Angiopoietins During Blood-Brain Barrier Breakdown and Angiogenesis","year":2003,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; University Health Network","funders":"Ontario Neurotrauma Foundation; Heart and Stroke Foundation of Canada","keywords":"Angiopoietin; Angiogenesis; Choroid plexus; Blood–brain barrier; Angiopoietin receptor; Autocrine signalling; Biology; Endothelial stem cell; Endocrinology; Internal medicine; Paracrine signalling; Tight junction; Fibronectin; Receptor; Vascular endothelial growth factor; Cell biology; Central nervous system; Medicine; Cancer research; Extracellular matrix; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001687031,0.0001297762,0.0001198872,0.00004650293,0.00008528912,0.00001243233,0.00006353802,0.0001360926,0.00004018635],"category_scores_gemma":[0.0001202181,0.0001271767,0.0000535714,0.0001494425,0.0001243801,0.000009945076,0.00003067115,0.00002970512,0.000001385364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006641954,"about_ca_system_score_gemma":0.00008867965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007174394,"about_ca_topic_score_gemma":0.000007029813,"domain_scores_codex":[0.9991578,0.0001161212,0.0001990481,0.0002735504,0.0001081765,0.0001453086],"domain_scores_gemma":[0.9994011,0.00001046177,0.0001181828,0.0002423281,0.0001181894,0.0001097288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001337029,0.00001386934,0.04933013,0.00003667101,0.00002343772,5.958794e-7,0.00009526372,0.00001553335,0.9496161,0.0001298631,0.0006786803,0.00004644021],"study_design_scores_gemma":[0.0003421211,0.00006055737,0.0333186,0.00002387655,0.00002663569,0.000004378814,0.00006561958,0.000002495048,0.961979,0.00006081765,0.003972626,0.0001432258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970971,0.002379462,0.0000636745,0.00005631114,0.00008133161,0.0001048717,0.00005660459,0.0000112008,0.0001494913],"genre_scores_gemma":[0.9980408,0.0001256495,0.00120228,0.000269541,0.0001270262,0.00002221736,0.00004293016,0.00002249554,0.0001470541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01601153,"threshold_uncertainty_score":0.5186116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006932541622924349,"score_gpt":0.2177385442621587,"score_spread":0.2108060026392344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}