{"id":"W2056371599","doi":"10.1053/gast.2000.16497","title":"Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice","year":2000,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":154,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Pathogenesis; Medicine; Mutant; Pharmacology; Immunology; Wild type; Chemistry; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004204061,0.00140152,0.0005128246,0.00200486,0.0005242514,0.000848261,0.000950436,0.001210497,0.002437381],"category_scores_gemma":[0.000315951,0.000634084,0.0008703616,0.0004811035,0.001416963,0.0009260601,0.0005622722,0.002189844,0.000599817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006967806,"about_ca_system_score_gemma":0.0003324993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009065121,"about_ca_topic_score_gemma":0.001354836,"domain_scores_codex":[0.999541,0.00008003062,0.00009023574,0.0001038161,0.0000960569,0.00008885794],"domain_scores_gemma":[0.9994898,0.00007324748,0.0002435109,0.00004328638,0.00002876036,0.0001213477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007837951,0.0001185867,0.0002952159,0.00005712656,0.00002110551,0.000254628,0.00005356956,0.0002073843,0.9956839,0.001651285,0.00006957346,0.0008038535],"study_design_scores_gemma":[0.000223005,0.0005230501,0.00402208,0.00004896132,0.0001026333,0.001448719,0.0001502575,0.0024319,0.9875051,0.0007315549,0.00278745,0.00002524149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848006,0.001433162,0.009421146,0.000455842,0.0001221647,0.0001374072,0.0014114,0.0002592172,0.001959074],"genre_scores_gemma":[0.9813707,0.001892377,0.01001054,0.0001425298,0.00003786383,0.0002305173,0.0009416051,0.000166014,0.0052077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002437381,"threshold_uncertainty_score":0.008153856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01419572185800085,"score_gpt":0.2550315776856319,"score_spread":0.2408358558276311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}