{"id":"W2056392188","doi":"10.1016/s0008-4182(05)80078-x","title":"Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration","year":2005,"lang":"en","type":"review","venue":"Canadian Journal of Ophthalmology","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":270,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Macular degeneration; Angiogenesis; Bevacizumab; Pegaptanib; Medicine; Vascular endothelial growth factor; Neovascularization; Choroidal neovascularization; Cancer research; Angiopoietin receptor; Vascular endothelial growth factor A; Internal medicine; Ranibizumab; Ophthalmology; Chemotherapy; VEGF receptors","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008077426,0.001047185,0.002441015,0.002692216,0.0004632498,0.001145142,0.001117326,0.001572018,0.003500097],"category_scores_gemma":[0.0007755303,0.0003284317,0.0005538424,0.00249587,0.000648976,0.001175298,0.0005415985,0.002060053,0.002364874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000817484,"about_ca_system_score_gemma":0.001412897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004131631,"about_ca_topic_score_gemma":0.01026667,"domain_scores_codex":[0.9997495,0.00002872594,0.00003222523,0.00003551279,0.0001291862,0.00002490348],"domain_scores_gemma":[0.9995993,0.0001787542,0.00005910444,0.00000961354,0.0001087868,0.00004446401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001049403,0.0001478669,0.0001360927,0.01047885,0.00009377277,0.0004363021,0.00004989638,0.0002636577,0.002610686,0.002036091,0.02703935,0.9566024],"study_design_scores_gemma":[0.00008091004,0.0001883187,0.001159099,0.002916517,0.0002014553,0.002719339,0.00007067342,0.0001289031,0.001069055,0.001357093,0.9900826,0.00002599734],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001031039,0.9983672,0.0001628016,0.0001728088,0.0001897984,0.000006841006,0.0000103208,0.000007369838,0.0009797284],"genre_scores_gemma":[0.0006073334,0.9979889,0.0002850803,0.0001670004,0.0001370031,0.000007071601,0.00001798414,0.000001024488,0.0007886682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004131631,"threshold_uncertainty_score":0.01170903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06514762321699069,"score_gpt":0.351214328748123,"score_spread":0.2860667055311323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}