{"id":"W2056424275","doi":"10.1016/j.bcp.2003.10.005","title":"Ca2+ influx is not involved in acute cytotoxicity of arachidonic acid","year":2003,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ontario Neurotrauma Foundation","keywords":"Nordihydroguaiaretic acid; Extracellular; Arachidonic acid; Chemistry; Biochemistry; Intracellular; Calcium; Programmed cell death; Pharmacology; Biology; Enzyme; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003577639,0.0005158997,0.0008736341,0.00045486,0.0006791759,0.0007760552,0.0007137546,0.0010766,0.002419651],"category_scores_gemma":[0.0006935978,0.0003552145,0.0004960941,0.0004867718,0.0008838434,0.001224475,0.0004563278,0.001217897,0.0008428491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000768561,"about_ca_system_score_gemma":0.0007705803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001927684,"about_ca_topic_score_gemma":0.002231098,"domain_scores_codex":[0.9995627,0.00005700443,0.00004655118,0.00004438164,0.0001129695,0.0001763154],"domain_scores_gemma":[0.9991854,0.0001664984,0.0001388999,0.0002548792,0.0001329244,0.0001213596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002533012,0.00008917545,0.0009387744,0.00009547978,0.00001542106,0.000582965,0.00005545172,0.00006228584,0.9936247,0.0002852381,0.00006076616,0.001656662],"study_design_scores_gemma":[0.00008914456,0.0006444537,0.01489396,0.00001324556,0.00004877313,0.001203971,0.0001191832,0.0005765381,0.981365,0.000172939,0.0008622848,0.00001038844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990374,0.002920671,0.002614539,0.0001926118,0.0000772006,0.00005565537,0.0003779049,0.0001151335,0.003272299],"genre_scores_gemma":[0.997162,0.0004615242,0.0003997722,0.00002914509,0.00001569223,0.00002816532,0.0003714337,0.000009018641,0.001523232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002419651,"threshold_uncertainty_score":0.008094549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01715206827015813,"score_gpt":0.2897792642158492,"score_spread":0.272627195945691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}