{"id":"W2056428844","doi":"10.1371/journal.pone.0011161","title":"Blockade of TRPM7 Channel Activity and Cell Death by Inhibitors of 5-Lipoxygenase","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences; School of Medicine, Vanderbilt University; Queen's University; National Institutes of Health; Vanderbilt University","keywords":"TRPM7; HEK 293 cells; Arachidonate 5-lipoxygenase; Zileuton; Intracellular; Chemistry; Cell culture; Ion channel; Cell biology; Lipoxygenase; Pharmacology; Biochemistry; Biology; Arachidonic acid; Enzyme; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958886,0.000405567,0.0003588098,0.000228598,0.0001571004,0.0002686114,0.0002673564,0.0002758032,0.0009347929],"category_scores_gemma":[0.0001334036,0.00009590046,0.0004528651,0.0001391131,0.0001873523,0.0002277107,0.0001870444,0.0007822068,0.0002393918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002198045,"about_ca_system_score_gemma":0.0002106164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000212867,"about_ca_topic_score_gemma":0.0003965705,"domain_scores_codex":[0.9998306,0.00003147111,0.00002062814,0.00002538529,0.00003662042,0.00005525823],"domain_scores_gemma":[0.9999276,0.00002380678,0.0000205212,0.000007966018,0.000008341908,0.00001170827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001849714,0.00008752937,0.0001219494,0.000106707,0.00001280417,0.00007551003,0.0000149276,0.00006627105,0.9961909,0.000191743,0.00008108448,0.002865532],"study_design_scores_gemma":[0.00004354586,0.0007436133,0.002091929,0.000009710743,0.0000290247,0.0001963901,0.00002086742,0.0008428268,0.9935935,0.00005266582,0.002372131,0.000003780096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776399,0.009198688,0.009164503,0.0003576208,0.0001192852,0.0001539603,0.0003886026,0.0001662694,0.002811095],"genre_scores_gemma":[0.9902957,0.00464504,0.003162583,0.0001036927,0.00003172924,0.0001371701,0.0003678264,0.00001149049,0.001244772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009347929,"threshold_uncertainty_score":0.003127158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02327365879735501,"score_gpt":0.2362814174779918,"score_spread":0.2130077586806367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}