{"id":"W2056441411","doi":"10.1182/blood-2005-03-0916","title":"Platelets express functional Toll-like receptor-4","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":480,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arthritis Research Centre of Canada; University of Calgary; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Canadian Association of Gastroenterology; Fondation pour la Recherche Médicale; AstraZeneca","keywords":"Platelet; TLR4; Immunology; Platelet activation; Lipopolysaccharide; Receptor; P-selectin; Biology; Sepsis; Toll-like receptor; Protease-activated receptor; Chemistry; Internal medicine; Endocrinology; Inflammation; Innate immune system; Thrombin; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224684,0.0002839678,0.0001719704,0.0002785231,0.0001143724,0.0003483734,0.0001065227,0.0003348419,0.002018689],"category_scores_gemma":[0.0003374019,0.0001442777,0.0001382358,0.0001407848,0.0001227567,0.0001327302,0.000247313,0.0004482167,0.0006046445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001404889,"about_ca_system_score_gemma":0.00008524792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000162178,"about_ca_topic_score_gemma":0.0001260013,"domain_scores_codex":[0.999819,0.00005072598,0.00002364824,0.00002461865,0.0000515929,0.00003055137],"domain_scores_gemma":[0.9998255,0.0000337825,0.00007369003,0.00002246373,0.00002088529,0.0000237214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004411782,0.00002780635,0.006136384,0.00009591439,0.00003744359,0.001084807,0.00004296119,0.00006886175,0.9791114,0.0003153119,0.000470278,0.01216767],"study_design_scores_gemma":[0.0001580422,0.001841864,0.1236355,0.00007897505,0.0002406051,0.03173283,0.0001780333,0.001559536,0.8110205,0.001012981,0.02851099,0.0000301601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855196,0.006238808,0.004080453,0.0004535941,0.00003728806,0.00002392913,0.0006370047,0.0001148487,0.002894515],"genre_scores_gemma":[0.9939711,0.001319983,0.001733216,0.0001295457,0.00002711233,0.00002212147,0.001063954,0.00001094608,0.001721966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002018689,"threshold_uncertainty_score":0.006753206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0583398034036459,"score_gpt":0.2888540818681861,"score_spread":0.2305142784645402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}