{"id":"W2056447191","doi":"10.1038/ncomms6276","title":"Autophagy supports genomic stability by degrading retrotransposon RNA","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"Stem Cell Network; Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; J.P. Bickell Foundation","keywords":"Retrotransposon; Biology; RNA; Autophagy; Genetics; Genome; Gene; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003319315,0.0001485663,0.0002409184,0.00006062002,0.0002577457,0.00001856191,0.0005448905,0.0002848123,0.0002760794],"category_scores_gemma":[0.00012067,0.0001372473,0.0001354123,0.0001919812,0.0001548757,0.00007774556,0.00006954514,0.0009371865,0.00004003324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001130472,"about_ca_system_score_gemma":0.00008902855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001946015,"about_ca_topic_score_gemma":0.00002847553,"domain_scores_codex":[0.9989507,0.0001601885,0.0002584385,0.0002284002,0.0001816952,0.0002205712],"domain_scores_gemma":[0.9970797,0.0001948979,0.00008470524,0.002360892,0.0001008974,0.0001788513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004501492,0.00291597,0.116565,0.0002360599,0.0006801566,0.00001612698,0.002189612,0.000003331238,0.7085834,0.05834063,0.05202537,0.05799422],"study_design_scores_gemma":[0.002693782,0.0003144277,0.3024063,0.0001108453,0.0003881905,0.00004138329,0.0001154339,0.002118369,0.1225814,0.003017816,0.5656704,0.0005416147],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9572638,0.01632117,0.0005030226,0.006327492,0.0001787141,0.0004996496,0.00007045437,0.0002701171,0.01856559],"genre_scores_gemma":[0.9940555,0.0007246597,0.002603801,0.001743561,0.0000703591,0.00004098804,0.0004254642,0.00002938647,0.0003062455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5860019,"threshold_uncertainty_score":0.5596782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01740414635423839,"score_gpt":0.3021817075657174,"score_spread":0.2847775612114791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}