{"id":"W2056460689","doi":"10.1111/jth.12807","title":"Recommendations for the development of new anticoagulant drugs for pediatric use: communication from the SSC of the ISTH","year":2014,"lang":"en","type":"review","venue":"Journal of Thrombosis and Haemostasis","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McMaster Children's Hospital","funders":"","keywords":"Medicine; Hemostasis; Intensive care medicine; Anticoagulant; Venous thromboembolism; Standardization; Thrombosis; License; Computer science; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001419725,0.0001691087,0.001136313,0.0000370762,0.0004139811,0.00003813771,0.0003980372,0.00008360528,0.00003112797],"category_scores_gemma":[0.0006217307,0.00006606539,0.0005278038,0.0001602611,0.00008557164,0.00007422772,0.0001503865,0.0003088375,3.407908e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004295967,"about_ca_system_score_gemma":0.0003326012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000690281,"about_ca_topic_score_gemma":0.00002816965,"domain_scores_codex":[0.9982705,0.0001815217,0.001088709,0.0000978605,0.0002390645,0.0001223824],"domain_scores_gemma":[0.9902456,0.006897072,0.002177137,0.0003389881,0.0002800396,0.00006118779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006195797,0.00009884552,0.0002325907,0.002126712,0.001766223,1.993743e-8,0.001126595,2.365766e-7,0.000001001801,0.00009159606,0.05781795,0.9366763],"study_design_scores_gemma":[0.0006773508,0.00007715637,0.001475258,0.002705944,0.01031806,0.000004566598,0.0004179515,0.00001095509,0.00002180665,0.00009390353,0.9841244,0.00007263187],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003861471,0.9726076,0.0008697868,0.02462117,0.0002514718,0.001060537,0.0001792414,0.000001646802,0.00002236929],"genre_scores_gemma":[0.0006621574,0.9900207,0.008594163,0.0003634844,0.0002736955,0.00002004888,0.0000218595,0.00001676268,0.00002710859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9366037,"threshold_uncertainty_score":0.318405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4442125251413291,"score_gpt":0.4920589740250084,"score_spread":0.04784644888367928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}