{"id":"W2056469580","doi":"10.1016/j.cellsig.2004.11.006","title":"A-Raf associates with and regulates platelet-derived growth factor receptor signalling","year":2004,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation; Saskatchewan Cancer Agency","keywords":"Autophosphorylation; Platelet-derived growth factor receptor; GRB2; Cell biology; Receptor tyrosine kinase; Growth factor receptor; Tyrosine kinase; Chemistry; Tyrosine phosphorylation; Tropomyosin receptor kinase C; MAPK/ERK pathway; Cancer research; Signal transduction; Biology; Phosphorylation; Growth factor; Biochemistry; Receptor; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000173095,0.0004332406,0.0001675431,0.000495364,0.0007017968,0.0008065189,0.0004282827,0.0004380266,0.002075186],"category_scores_gemma":[0.0002895979,0.0003979818,0.0004279985,0.0002516211,0.0003014262,0.0006858603,0.0006593723,0.000726092,0.002065597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005343375,"about_ca_system_score_gemma":0.0001664887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006365424,"about_ca_topic_score_gemma":0.0008079711,"domain_scores_codex":[0.9997045,0.00003864399,0.00001116707,0.00004760904,0.00007685919,0.0001211397],"domain_scores_gemma":[0.9998865,0.00001892446,0.00002773969,0.0000138232,0.00001907294,0.0000339023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003617477,0.00004416728,0.0006519976,0.00005753296,0.00001428705,0.0003019705,0.00003227531,0.0001234286,0.9948573,0.001000955,0.0002048643,0.002349514],"study_design_scores_gemma":[0.00006120616,0.0002010411,0.04068248,0.00002207066,0.00004242895,0.002775096,0.0002234025,0.00439238,0.9340626,0.001204786,0.01629599,0.00003653347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854575,0.003950946,0.002882649,0.0003507818,0.00005996696,0.00002024722,0.0001995503,0.0001215275,0.006956797],"genre_scores_gemma":[0.9909558,0.001459018,0.001270942,0.00008487287,0.00003243251,0.00001985218,0.0004701702,0.00003372676,0.005673112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002075186,"threshold_uncertainty_score":0.006942213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00993843304290545,"score_gpt":0.1904841164186484,"score_spread":0.1805456833757429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}