{"id":"W2056494524","doi":"10.1089/hum.2008.134","title":"<i>let-7</i> MicroRNA Transfer in Pancreatic Cancer-Derived Cells Inhibits <i>In Vitro</i> Cell Proliferation but Fails to Alter Tumor Progression","year":2009,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Centre Hospitalier Universitaire de Toulouse; Institut National Du Cancer; Centre Hospitalier Universitaire de Bordeaux; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; University of Nebraska Medical Center","keywords":"Pancreatic cancer; microRNA; Cancer research; Oncogene; Cancer; Biology; Transfection; Cancer cell; Cell growth; Cell culture; Molecular biology; Cell cycle; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001556099,0.0002697037,0.0002437788,0.0001218008,0.00006840952,0.00005440865,0.0001727655,0.0001233763,0.00003067112],"category_scores_gemma":[0.000002391588,0.0002615121,0.00008238381,0.0001621304,0.00002842584,0.00001494358,0.00001770772,0.0001002329,0.00001026541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006768883,"about_ca_system_score_gemma":0.00008005297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003550324,"about_ca_topic_score_gemma":0.00007425961,"domain_scores_codex":[0.9984199,0.0001313991,0.0003855467,0.0005232489,0.0001639857,0.0003759418],"domain_scores_gemma":[0.999435,0.000003746464,0.00006393933,0.0003291655,0.00005731015,0.000110855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007018949,0.0002806077,0.0002715152,0.00002001781,0.000008604042,0.000008916838,0.0003319942,0.0001712195,0.9949006,0.000001387762,0.0002008159,0.003102427],"study_design_scores_gemma":[0.002122806,0.0003666387,0.003824554,0.00005588608,0.000007215731,0.000003394565,0.00001899756,0.00002969577,0.9924488,0.00002995239,0.0007845982,0.0003074569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960892,0.001872059,0.0002557985,0.0003054537,0.00005046458,0.001315048,0.00002298238,0.0000203237,0.0000686701],"genre_scores_gemma":[0.9965951,0.0002429296,0.0005195899,0.001905807,0.0002168325,0.0001938304,0.000181063,0.00003951772,0.0001052745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003553039,"threshold_uncertainty_score":0.9999837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01101408332936017,"score_gpt":0.2626346644866676,"score_spread":0.2516205811573075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}