{"id":"W2056494920","doi":"10.3354/dao044017","title":"Recombinant vaccines against infectious hematopoietic necrosis virus: production by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials","year":2001,"lang":"en","type":"article","venue":"Diseases of Aquatic Organisms","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Oregon Sea Grant, Oregon State University; U.S. Department of Agriculture; Western Regional Aquaculture Center; National Oceanic and Atmospheric Administration; U.S. Department of Commerce","keywords":"Biology; Infectious hematopoietic necrosis virus; Caulobacter crescentus; Microbiology; Fusion protein; Virology; S-layer; Recombinant DNA; Secretion; Rainbow trout; Bacteria; Biochemistry; Bacterial protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001816808,0.0007452665,0.0004931277,0.0003349974,0.0002884994,0.0004412565,0.0005785868,0.0007421181,0.0003985401],"category_scores_gemma":[0.0009867046,0.0002020788,0.0003542933,0.0002260271,0.0004260287,0.0003906895,0.0002339687,0.0006991973,0.000148829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007592009,"about_ca_system_score_gemma":0.0005392434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378982,"about_ca_topic_score_gemma":0.001546948,"domain_scores_codex":[0.9992297,0.0002600303,0.0000709853,0.0001042474,0.0002566729,0.00007830351],"domain_scores_gemma":[0.9994817,0.0001314061,0.0001423195,0.00006542207,0.00009214955,0.00008706848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004947433,0.0005138292,0.0004865999,0.0001467185,0.0000281682,0.00006833378,0.00004829112,0.000523475,0.9947422,0.00005278548,0.00004538197,0.002849546],"study_design_scores_gemma":[0.0003493799,0.01148796,0.001610584,0.00001819035,0.00005745172,0.0002630024,0.00002210675,0.0006691284,0.9841115,0.0000300058,0.001370584,0.00001000574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937628,0.00128254,0.004102617,0.00007570478,0.00002199329,0.0003016156,0.0001607005,0.00004019324,0.0002517594],"genre_scores_gemma":[0.9790545,0.001754009,0.01674381,0.00005891451,0.0000255585,0.0002359535,0.00132047,0.00003041525,0.0007764236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001816808,"threshold_uncertainty_score":0.009608328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01245387855706632,"score_gpt":0.2457281215376103,"score_spread":0.233274242980544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}