{"id":"W2056494920","doi":"10.3354/dao044017","title":"Recombinant vaccines against infectious hematopoietic necrosis virus: production by the Caulobacter crescentus S-layer protein secretion system and evaluation in laboratory trials","year":2001,"lang":"en","type":"article","venue":"Diseases of Aquatic Organisms","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Oregon Sea Grant, Oregon State University; U.S. Department of Agriculture; Western Regional Aquaculture Center; National Oceanic and Atmospheric Administration; U.S. Department of Commerce","keywords":"Biology; Infectious hematopoietic necrosis virus; Caulobacter crescentus; Microbiology; Fusion protein; Virology; S-layer; Recombinant DNA; Secretion; Rainbow trout; Bacteria; Biochemistry; Bacterial protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001102715,0.0002442793,0.0004634889,0.000123721,0.0001756408,0.00004511856,0.0001386541,0.0001425814,0.0002178048],"category_scores_gemma":[0.0005883392,0.000170065,0.00009205069,0.0003585923,0.0001085017,0.0001780299,0.00006188492,0.0001210305,0.00006712336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296549,"about_ca_system_score_gemma":0.00008202063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001394927,"about_ca_topic_score_gemma":0.00008442369,"domain_scores_codex":[0.9975809,0.00102866,0.0006479094,0.0003821189,0.0001065736,0.000253808],"domain_scores_gemma":[0.9989778,0.00008919749,0.000418686,0.000336073,0.0001433005,0.00003490691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003250064,0.0005687714,0.01295524,0.0002975125,0.0002361292,0.000003183491,0.0007018597,0.000008050883,0.975734,0.000115298,0.00607428,0.002980653],"study_design_scores_gemma":[0.02130292,0.001080937,0.1187958,0.003073715,0.005476309,0.00007102123,0.01392733,0.0003238184,0.8247804,0.001544268,0.007525184,0.002098228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896948,0.006718578,0.00004711524,0.0004549552,0.0004994512,0.002383964,0.0000709118,0.00007033977,0.00005986927],"genre_scores_gemma":[0.9986825,0.0002698813,0.000005624644,0.00007709082,0.00003538902,0.0001754025,0.0004346085,0.00002386083,0.0002956536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1509536,"threshold_uncertainty_score":0.693505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01245387855706632,"score_gpt":0.2457281215376103,"score_spread":0.233274242980544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}