{"id":"W2056497433","doi":"10.1016/j.fob.2013.09.006","title":"Intramolecular clasp of the cellulosomal <i>Ruminococcus flavefaciens</i> ScaA dockerin module confers structural stability","year":2013,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Israeli Centers for Research Excellence; Israel Science Foundation; Weizmann Institute of Science; United States-Israel Binational Science Foundation; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Cellulosome; Chemistry; Biochemistry; Ruminococcus; Protein structure; Biology; Computational biology; Biophysics; Cellulase; Enzyme; Clostridium thermocellum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115173,0.0002885671,0.0001706264,0.00009243937,0.0001105391,0.0002524952,0.0001994184,0.0001567922,0.000525894],"category_scores_gemma":[0.0001876478,0.00008326109,0.0001752437,0.0001150674,0.0001450838,0.0001513708,0.0002935636,0.0004551031,0.0002219613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002753718,"about_ca_system_score_gemma":0.000181258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001134088,"about_ca_topic_score_gemma":0.001375706,"domain_scores_codex":[0.9999278,0.00001340485,0.000006438159,0.00001883997,0.00001674441,0.00001680758],"domain_scores_gemma":[0.9998614,0.00002566693,0.00004721325,0.00002466847,0.00001310473,0.00002801805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006923249,0.00002411027,0.000571228,0.00001157424,0.000004545947,0.0000618327,0.00001733649,0.0002226638,0.9973665,0.0001001837,0.0000179403,0.001532943],"study_design_scores_gemma":[0.00001150224,0.0001458203,0.005112278,0.000005057263,0.00001281577,0.0003273637,0.00004640888,0.003185805,0.9894739,0.00005769315,0.001615973,0.000005282734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975688,0.00008912307,0.001793459,0.00001760711,0.000002846525,0.00000623964,0.00005288163,0.00003458998,0.000434359],"genre_scores_gemma":[0.9978861,0.00004264974,0.001464613,0.000007555218,0.000001389125,0.00000397583,0.0001701403,0.00001196339,0.0004116219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001134088,"threshold_uncertainty_score":0.002255023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200754645239243,"score_gpt":0.2302900204556359,"score_spread":0.2182824740032435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}