{"id":"W2056522696","doi":"10.1016/j.ymgme.2011.07.023","title":"Increased superoxide accumulation in pyruvate dehydrogenase complex deficient fibroblasts","year":2011,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; University of Toronto","keywords":"Pyruvate dehydrogenase complex; Chemistry; Superoxide; Lactate dehydrogenase; Cell biology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002574091,0.0006685969,0.0004868003,0.0005607289,0.0003464838,0.0006157244,0.0003005553,0.0005680397,0.002389492],"category_scores_gemma":[0.0002362998,0.0003447882,0.0003526564,0.0003527085,0.0003275571,0.0003864727,0.0002948174,0.001053282,0.0006114216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002405383,"about_ca_system_score_gemma":0.0002465763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009173908,"about_ca_topic_score_gemma":0.000639814,"domain_scores_codex":[0.9996343,0.00004671618,0.00006651154,0.00008867609,0.0001080311,0.00005571128],"domain_scores_gemma":[0.9995028,0.0001090519,0.00008005405,0.00009561335,0.00005963574,0.0001528266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001218669,0.00001932197,0.0001592605,0.00001624417,0.00000476505,0.0002195912,0.00001965228,0.00002221469,0.9990614,0.00006151528,0.00001927607,0.0002748998],"study_design_scores_gemma":[0.000028968,0.000176562,0.004063964,0.000004184595,0.00002655943,0.001092955,0.00007322907,0.0003442141,0.993238,0.00008720368,0.0008585901,0.000005611346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914764,0.00127564,0.00445063,0.0002050477,0.0001494924,0.00001920437,0.0008393674,0.0001474875,0.001436748],"genre_scores_gemma":[0.9938524,0.000509425,0.001500852,0.00006533163,0.00001960667,0.00002769161,0.0005011007,0.00003636974,0.003487328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002389492,"threshold_uncertainty_score":0.007993639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03780829644134986,"score_gpt":0.259992899953339,"score_spread":0.2221846035119891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}