{"id":"W2056573634","doi":"10.1038/nrmicro2522","title":"Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":343,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Health Canada; National Institutes of Health; Burroughs Wellcome Fund","keywords":"Biology; Cryptococcus neoformans; Cryptococcus; Fungal pathogen; Cryptococcus gattii; Fungus; Pathogen; Opportunistic pathogen; Cryptococcosis; Microbiology; Adaptation (eye); Gene; Genetics; Virulence; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006937539,0.0006632198,0.004513265,0.0001947478,0.0001628109,0.000006899987,0.0003851196,0.001553166,0.0002503843],"category_scores_gemma":[0.000414539,0.0003277218,0.001967575,0.0003745276,0.0002853344,0.00001968138,0.0002757977,0.001837631,0.0001620573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001279836,"about_ca_system_score_gemma":0.0003333345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005643462,"about_ca_topic_score_gemma":0.00001605195,"domain_scores_codex":[0.9969274,0.000639361,0.001380571,0.0005815816,0.00005727442,0.0004138335],"domain_scores_gemma":[0.9974042,0.0001877215,0.001150117,0.0009909568,0.0001728789,0.00009415102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001536202,0.0001737657,0.0001080416,0.04628441,0.0007823313,0.00002783877,0.00007177714,3.197385e-9,0.001448228,0.0007034413,0.02452834,0.9258565],"study_design_scores_gemma":[0.0001611677,0.0001248805,0.00002256122,0.02423518,0.00346728,0.0009778561,0.000005807365,1.140255e-8,0.00001837578,0.000009673258,0.9707046,0.0002726392],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003286448,0.9906513,0.00001320023,0.00003177885,0.002627614,0.002843024,0.0003363427,0.00003194073,0.003461532],"genre_scores_gemma":[0.00001853154,0.9967375,0.0002006515,0.000272808,0.0004408959,0.0003126736,0.0001858702,0.0000585039,0.001772564],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9461762,"threshold_uncertainty_score":0.9999175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08594527404116345,"score_gpt":0.367268478936628,"score_spread":0.2813232048954646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}