{"id":"W2056594696","doi":"10.1074/jbc.m113.536037","title":"Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; RIKEN; Japan Science and Technology Agency; University of Toronto; Ministry of Education, Culture, Sports, Science and Technology; Japan Society for the Promotion of Science; Keio University","keywords":"Reprogramming; Induced pluripotent stem cell; Telomerase reverse transcriptase; Somatic cell; Telomere; Cell biology; Telomerase; Biology; Stem cell; Cellular differentiation; Molecular biology; Embryonic stem cell; Cell; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006422594,0.0004204648,0.0003980467,0.0004100896,0.0001980225,0.0006120349,0.0003067316,0.0005976679,0.0008200583],"category_scores_gemma":[0.0003632453,0.0002262434,0.0003795369,0.0004740793,0.0003036374,0.0003305599,0.0003758841,0.0008072932,0.0007242254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002036008,"about_ca_system_score_gemma":0.0002172406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001387963,"about_ca_topic_score_gemma":0.000187762,"domain_scores_codex":[0.9995077,0.0001109697,0.00006773036,0.00009967736,0.0001615433,0.00005246145],"domain_scores_gemma":[0.9997647,0.00004972517,0.00006476232,0.00005826994,0.00003193137,0.0000305612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006773615,0.00003686581,0.0003468772,0.0002527927,0.00001475384,0.0002436676,0.00003302973,0.0002122873,0.9687355,0.00155366,0.0002789671,0.02822384],"study_design_scores_gemma":[0.00003547278,0.0003243564,0.001866213,0.00005899618,0.0000786794,0.002895188,0.00002906131,0.001264005,0.9410714,0.0007546698,0.05160121,0.0000208001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5800425,0.1771241,0.2062584,0.001415833,0.001495434,0.0003012692,0.001029273,0.001596588,0.03073665],"genre_scores_gemma":[0.9168503,0.04509457,0.02575554,0.0002463242,0.000236311,0.0001524563,0.001113986,0.0001072447,0.01044329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008200583,"threshold_uncertainty_score":0.00339663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142684353201849,"score_gpt":0.2625364449513527,"score_spread":0.2311096014193342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}