{"id":"W2056673221","doi":"10.1261/rna.157806","title":"Searching for IRES","year":2006,"lang":"en","type":"review","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Internal ribosome entry site; Biology; RNA; Computational biology; Translation (biology); Nucleic acid structure; Eukaryotic translation; Ribosome; Protein biosynthesis; Ribosome profiling; Genome; Nucleic acid secondary structure; Genetics; Messenger RNA; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001132984,0.001146915,0.002173246,0.00221476,0.0009490914,0.002727811,0.001766151,0.00257821,0.008905809],"category_scores_gemma":[0.003066791,0.0009927143,0.001893964,0.002606338,0.0006931412,0.004834606,0.0009808841,0.002129471,0.009093411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009979921,"about_ca_system_score_gemma":0.001107381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003230571,"about_ca_topic_score_gemma":0.0003366449,"domain_scores_codex":[0.9992185,0.00008907766,0.00008323389,0.0003094807,0.0002189032,0.00008081898],"domain_scores_gemma":[0.9985677,0.000624971,0.0003588142,0.0001384321,0.0002208186,0.00008926431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001245086,0.0003002877,0.02072079,0.01893588,0.00073616,0.003761342,0.0008048294,0.008798985,0.2618955,0.08689263,0.04973658,0.5461719],"study_design_scores_gemma":[0.0001661978,0.0005489969,0.009042995,0.00246897,0.0008739072,0.006469848,0.001017016,0.01572274,0.190212,0.0635678,0.7096643,0.0002451331],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1771525,0.4545524,0.2899905,0.006980928,0.002525523,0.000415917,0.01423802,0.007207598,0.04693663],"genre_scores_gemma":[0.35824,0.1570426,0.4024493,0.004456736,0.001158962,0.0005787821,0.0584778,0.0009234844,0.01667231],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008905809,"threshold_uncertainty_score":0.02979285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04810452435048155,"score_gpt":0.3466928383183128,"score_spread":0.2985883139678313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}