{"id":"W2056719642","doi":"10.1016/j.clim.2011.02.021","title":"Laquinimod in multiple sclerosis","year":2011,"lang":"en","type":"review","venue":"Clinical Immunology","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Multiple sclerosis; Tolerability; Medicine; Clinical trial; Immune system; Neuroscience; Disease; Immunology; Adverse effect; Pharmacology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00131191,0.0008686873,0.004684572,0.0005257215,0.000163886,0.00002017077,0.001582219,0.004567916,0.002946384],"category_scores_gemma":[0.001086084,0.000723673,0.001559343,0.0004490294,0.001085143,0.0001105423,0.0008130328,0.003634155,0.01566565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001216689,"about_ca_system_score_gemma":0.0003823874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001836747,"about_ca_topic_score_gemma":0.00009286469,"domain_scores_codex":[0.992143,0.002331865,0.003077142,0.001268629,0.00003266736,0.001146708],"domain_scores_gemma":[0.9954892,0.001892676,0.0009541799,0.001551582,0.00006454567,0.00004778974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000926405,0.0007292283,0.00005700649,0.0004430636,0.001046166,0.00001923776,0.00004707493,1.350469e-8,0.0001361846,0.001641497,0.0009346304,0.9948533],"study_design_scores_gemma":[0.001991651,0.0006438215,0.0004023747,0.004118786,0.0005243297,0.00008449322,0.0000298106,1.253797e-7,0.00004314504,0.0002478776,0.9912,0.0007136299],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002091107,0.9899889,0.00002970756,0.00001310505,0.007143966,0.001030652,0.0001071172,0.000176361,0.00130113],"genre_scores_gemma":[0.0002085951,0.9954014,0.0001862175,0.0001202293,0.0001064516,0.0003382166,0.0003991784,0.0001373292,0.003102366],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9941396,"threshold_uncertainty_score":0.9995214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2424120005845541,"score_gpt":0.3665807573270292,"score_spread":0.124168756742475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}