{"id":"W2056806024","doi":"10.1242/dev.02853","title":"<i>Drosophila</i>Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation","year":2007,"lang":"en","type":"article","venue":"Development","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Biology; Phosphorylation; Wnt signaling pathway; Cell biology; Signal transduction; SMAD; Nuclear export signal; Bone morphogenetic protein; Kinase; Protein-Serine-Threonine Kinases; Serine; Signal transducing adaptor protein; Protein kinase A; Genetics; Gene; Cell nucleus; Nucleus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007249597,0.000264803,0.0001060505,0.0001020366,0.0001175304,0.0001581221,0.0001747235,0.0001132955,0.001333077],"category_scores_gemma":[0.00005635415,0.0000846618,0.00014593,0.00004667952,0.0001809601,0.0001320211,0.0001778394,0.0002483639,0.0003627486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001894459,"about_ca_system_score_gemma":0.00007151593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003004393,"about_ca_topic_score_gemma":0.000570497,"domain_scores_codex":[0.9999444,0.000008268964,0.000006277499,0.000009843641,0.00001434149,0.00001687116],"domain_scores_gemma":[0.9999573,0.000006606316,0.00001722548,0.00000583919,0.00000321136,0.000009764621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003793482,0.00000486519,0.00008164419,0.00001646562,0.000001970456,0.00003880742,0.000002749113,0.00002206517,0.9991207,0.0001723759,0.00002822248,0.0004720638],"study_design_scores_gemma":[0.000004746087,0.00003535939,0.001347275,0.000001894574,0.000002827617,0.000158748,0.000005400543,0.000184341,0.9959875,0.00002929432,0.002241477,0.000001189607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871179,0.001449465,0.002920658,0.0001800747,0.00003716151,0.00001733294,0.000347318,0.0001054357,0.007824591],"genre_scores_gemma":[0.9946244,0.0006107496,0.001680968,0.00006027209,0.000008075175,0.00001191588,0.0003025437,0.00001858592,0.002682342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001333077,"threshold_uncertainty_score":0.00445962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0142490907790073,"score_gpt":0.2554247334744689,"score_spread":0.2411756426954616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}