{"id":"W2056822097","doi":"10.1021/ja903897e","title":"Measurement of Methyl Group Motional Parameters of Invisible, Excited Protein States by NMR Spectroscopy","year":2009,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Conformational isomerism; Excited state; Relaxation (psychology); Population; Nuclear magnetic resonance spectroscopy; Spectroscopy; Chemical physics; Crystallography; Dispersion (optics); Computational chemistry; Molecule; Stereochemistry; Atomic physics; Quantum mechanics; Physics; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003563146,0.0002437887,0.0002118538,0.0003598051,0.0002108171,0.0002469968,0.0003185773,0.0004481342,0.0005765065],"category_scores_gemma":[0.0009191174,0.000173557,0.0001382222,0.0002471153,0.0004081025,0.0004854732,0.0003304664,0.0008200532,0.0001275454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252754,"about_ca_system_score_gemma":0.0001410538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004507641,"about_ca_topic_score_gemma":0.0006205309,"domain_scores_codex":[0.9998494,0.00003281891,0.000007314701,0.00003533114,0.00005664475,0.00001846338],"domain_scores_gemma":[0.9996122,0.000159852,0.0001127075,0.0000453574,0.00002920589,0.00004073868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005450012,0.00001916118,0.000686353,0.00002625504,0.000005033814,0.00002411434,0.00004587987,0.0002989316,0.99524,0.0002932851,0.00002526898,0.003281327],"study_design_scores_gemma":[0.00002241259,0.0002664222,0.009799151,0.00001302864,0.00001792079,0.0002587971,0.00008117656,0.01167599,0.9762719,0.0007991803,0.0007623181,0.00003169847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562902,0.0005186175,0.04188978,0.00006017073,0.000008205978,0.00002265117,0.0001358412,0.0001014738,0.0009730368],"genre_scores_gemma":[0.965996,0.0007255205,0.03238471,0.00003378885,0.00001357585,0.00003967949,0.0001655549,0.00002534535,0.000615899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005765065,"threshold_uncertainty_score":0.001928568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006271101527226246,"score_gpt":0.2366062862349626,"score_spread":0.2303351847077363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}