{"id":"W2056825271","doi":"10.1007/s11010-009-0167-5","title":"Keratinocyte-releasable factors increased the expression of MMP1 and MMP3 in co-cultured fibroblasts under both 2D and 3D culture conditions","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"MMP1; MMP3; Fibroblast; Matrix metalloproteinase; Keratinocyte; Extracellular matrix; Wound healing; Matrix Metalloproteinase 3; Cell biology; Western blot; Dermis; Dermal fibroblast; Chemistry; Molecular biology; Gene expression; Biology; In vitro; Immunology; Anatomy; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009590787,0.0002359546,0.000191437,0.00002352433,0.0001207834,0.00003957743,0.0001035021,0.0002883527,0.00001205321],"category_scores_gemma":[0.00003230594,0.0001760623,0.00005846291,0.00006311909,0.0001770705,0.000008451254,0.00006974659,0.000150457,3.751745e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009441871,"about_ca_system_score_gemma":0.00003794821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001888326,"about_ca_topic_score_gemma":0.000001827936,"domain_scores_codex":[0.9989536,0.000067509,0.0002087212,0.0003976208,0.000135713,0.0002368069],"domain_scores_gemma":[0.9994547,0.000007755376,0.00008907705,0.0002784327,0.00003574141,0.0001342738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004361205,0.00005796271,0.0002265615,0.00004204905,0.0000175718,0.00000743345,0.00006626696,0.000007009859,0.998993,0.0001009986,0.000400902,0.00003656633],"study_design_scores_gemma":[0.0007366683,0.0001697994,0.0001597184,0.000078986,0.00002633495,0.00001957598,0.0003996065,0.00002351367,0.9974959,0.0004221795,0.0002474257,0.0002202489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935254,0.004915095,0.0006244309,0.0000814359,0.00001336535,0.000210588,0.00005520244,0.000007823561,0.0005666186],"genre_scores_gemma":[0.99878,0.000105816,0.000250229,0.000261576,0.00003937823,0.000009815226,0.0003788596,0.00001390031,0.0001604687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005254517,"threshold_uncertainty_score":0.7179612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004044258658083081,"score_gpt":0.2168952881797175,"score_spread":0.2128510295216344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}