{"id":"W2056835200","doi":"10.2165/00003088-200443080-00003","title":"Pharmacokinetic Profile of Intramuscular Fulvestrant in Advanced Breast Cancer","year":2004,"lang":"en","type":"article","venue":"Clinical Pharmacokinetics","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Fulvestrant; Medicine; Pharmacokinetics; Breast cancer; Cancer; Oncology; Pharmacotherapy; Pharmacology; Internal medicine; Tamoxifen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003252787,0.0002414921,0.0003541584,0.00006591636,0.00002653332,0.000007264589,0.00029814,0.000260382,0.00009605395],"category_scores_gemma":[0.00005642641,0.0002187302,0.0002252445,0.0002503593,0.0002585039,0.000006092208,0.0001045148,0.0004293924,0.00001594827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002272423,"about_ca_system_score_gemma":0.0001686151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001891979,"about_ca_topic_score_gemma":0.000003819714,"domain_scores_codex":[0.9980916,0.0001210466,0.0007542109,0.0004660465,0.0001889744,0.0003781486],"domain_scores_gemma":[0.999176,0.00003245484,0.0001830041,0.000298224,0.0001091772,0.0002011851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008271089,0.0009966287,0.01084586,0.0001142142,0.0001963536,0.0000502374,0.00003153482,0.01220373,0.9300213,0.0000665107,0.0005055079,0.04414098],"study_design_scores_gemma":[0.01397224,0.0009569296,0.05582311,0.0002098232,0.0002207338,0.00006418648,0.00002781513,0.0005932811,0.9218423,0.0001703965,0.005513432,0.000605759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938933,0.003894339,0.0001869561,0.0004162024,0.000596748,0.000479551,0.00006870112,0.00001962134,0.0004446097],"genre_scores_gemma":[0.9917972,0.006393491,0.0008738479,0.0003629897,0.0003641627,0.00004571033,0.00005043639,0.0000419897,0.00007013457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04497724,"threshold_uncertainty_score":0.8919559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01371558393981914,"score_gpt":0.3546423921816309,"score_spread":0.3409268082418118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}