{"id":"W2056852956","doi":"10.1016/j.pharep.2014.12.008","title":"Characterization and preliminary anticonvulsant assessment of some 1,3,4-thiadiazole derivatives","year":2014,"lang":"en","type":"article","venue":"Pharmacological Reports","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Health Services and Policy Research","keywords":"ED50; Anticonvulsant; Pharmacology; Chemistry; Thiadiazoles; Stereochemistry; Epilepsy; Medicine; Medicinal chemistry; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009726406,0.0002450277,0.0001788698,0.0002259002,0.0001857406,0.0001106826,0.0001685719,0.0001667975,0.001328735],"category_scores_gemma":[0.0001941163,0.00008665535,0.0001720092,0.00026301,0.0001561812,0.0001281045,0.00008181299,0.0002979815,0.0002439407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638358,"about_ca_system_score_gemma":0.0002674895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001817736,"about_ca_topic_score_gemma":0.003226454,"domain_scores_codex":[0.999951,0.000009891529,0.000004898016,0.000007169218,0.00001401884,0.00001295527],"domain_scores_gemma":[0.9999189,0.0000160781,0.00001548119,0.000008593798,0.00002459171,0.00001633945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008207069,0.00002082479,0.0001188223,0.00004165043,0.000003858401,0.00006910367,0.00002942839,0.00006028841,0.9978061,0.00002952317,0.00002957485,0.001708771],"study_design_scores_gemma":[0.00001693556,0.001186859,0.004894091,0.00000583722,0.00003762754,0.0003602235,0.00003664149,0.0002787733,0.9909492,0.000024336,0.002204498,0.000004986995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910746,0.003891258,0.002815977,0.0001012339,0.00001441322,0.00005570941,0.0004241765,0.0000397027,0.001582932],"genre_scores_gemma":[0.9881971,0.004524988,0.002962074,0.00003667067,0.00001623122,0.00003730937,0.001112344,0.00001247573,0.003100687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001817736,"threshold_uncertainty_score":0.004445076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01492575021887839,"score_gpt":0.2950886687464992,"score_spread":0.2801629185276208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}