{"id":"W2056868141","doi":"10.1038/sj.cdd.4402246","title":"Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia","year":2007,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Matrix metalloproteinase; Programmed cell death; Ischemia; Apoptosis; Cell biology; Neuroscience; Biology; Chemistry; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000573521,0.0006079299,0.0007629021,0.0004284346,0.0003249807,0.000628612,0.0003960316,0.0004656698,0.001578986],"category_scores_gemma":[0.000566384,0.0002855255,0.0006764876,0.0002845828,0.0006333831,0.0006673444,0.0003820731,0.001409427,0.0003988464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007075669,"about_ca_system_score_gemma":0.0004761004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009584347,"about_ca_topic_score_gemma":0.001584125,"domain_scores_codex":[0.9996184,0.0000627742,0.0000433763,0.00003547178,0.00006662279,0.0001733795],"domain_scores_gemma":[0.9995722,0.00007100516,0.0001295278,0.00007821347,0.00004173183,0.0001073066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002981336,0.000130298,0.0002622122,0.0001338692,0.00002130735,0.0003654786,0.00009219563,0.0000980683,0.9931236,0.0004620023,0.0001329247,0.002196815],"study_design_scores_gemma":[0.0001130228,0.0007361323,0.005621343,0.00001553491,0.00005715695,0.0005503639,0.0001114096,0.0009321762,0.9907469,0.0002498566,0.0008553796,0.00001080051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923644,0.002368925,0.003064961,0.0001764571,0.0001228616,0.000046675,0.000201759,0.0001347023,0.001519185],"genre_scores_gemma":[0.9960729,0.0007828497,0.001084421,0.00004693735,0.00004623747,0.00004965072,0.0001519294,0.00001349998,0.001751727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001578986,"threshold_uncertainty_score":0.005282223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01013472803416863,"score_gpt":0.2261387587671399,"score_spread":0.2160040307329713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}