{"id":"W2056898744","doi":"10.1074/jbc.m109.058719","title":"Dual Modes of Interaction between XRCC4 and Polynucleotide Kinase/Phosphatase","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary; University of Alberta","funders":"University of Toronto; Fondation pour la Recherche Médicale; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Alberta Cancer Foundation; University of Calgary","keywords":"DNA repair protein XRCC4; DNA ligase; Non-homologous end joining; Phosphorylation; Biology; DNA repair; Serine hydroxymethyltransferase; Biochemistry; Cell biology; DNA; DNA mismatch repair; Serine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001926481,0.0001141412,0.0002104061,0.00001564445,0.00002706746,0.00001200023,0.0001319704,0.0002487271,0.00004310338],"category_scores_gemma":[0.0001921009,0.00008433407,0.0001127207,0.0000317846,0.00014199,0.000006006142,0.00009104025,0.0002812352,5.871209e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005184846,"about_ca_system_score_gemma":0.00003266856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004576027,"about_ca_topic_score_gemma":0.000001597936,"domain_scores_codex":[0.9992989,0.00001734818,0.0003432605,0.0001412986,0.00007349715,0.000125708],"domain_scores_gemma":[0.9993234,0.00002928999,0.0003003947,0.0001364444,0.0001011677,0.0001092797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001056136,0.00005810542,0.01385652,0.00001966524,0.00004816155,0.000006072415,0.000005269461,0.000002684246,0.9826008,0.00001315665,0.0002539551,0.003029983],"study_design_scores_gemma":[0.0003451657,0.0002183398,0.004505442,0.00001589541,0.00002539194,0.000143666,0.00007518425,0.000008979234,0.990672,0.00006844297,0.00382391,0.00009758532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988959,0.0005246109,0.0001400583,0.00006519732,0.00006845375,0.0000300796,0.00005002742,0.000002523861,0.0002231792],"genre_scores_gemma":[0.9981814,0.0003269372,0.0009087818,0.00004371215,0.0004435033,6.821935e-7,0.00004980484,0.00000678793,0.00003841454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009351075,"threshold_uncertainty_score":0.3439044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01285865054548268,"score_gpt":0.2583546073589151,"score_spread":0.2454959568134324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}