{"id":"W2056954750","doi":"10.1371/journal.pone.0110994","title":"TPX2 Impacts Acetylation of Histone H4 at Lysine 16: Implications for DNA Damage Response","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Österreichischen Akademie der Wissenschaften; University of Calgary; Alberta Innovates; Alberta Innovates - Health Solutions; Canadian Institutes of Health Research; Alberta Cancer Foundation","keywords":"Acetylation; Chromatin; Histone; Biology; Histone H4; DNA damage; Cell biology; Histone H3; Interphase; DAPI; DNA repair; Cohesin; Lysine; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001081277,0.0004830677,0.0002375211,0.0001323203,0.0002464123,0.000461561,0.0002115307,0.0003365116,0.00201098],"category_scores_gemma":[0.00008893824,0.0001323063,0.0001815984,0.0001151117,0.0002479455,0.0002848847,0.0002521579,0.0003862868,0.0002239918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002299428,"about_ca_system_score_gemma":0.0001425144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003361141,"about_ca_topic_score_gemma":0.0004880271,"domain_scores_codex":[0.9999291,0.00000871026,0.000005642859,0.00002629117,0.00001722557,0.00001307522],"domain_scores_gemma":[0.9999357,0.000008752093,0.00001803335,0.000007377912,0.000006427266,0.00002363565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001052913,0.00001375886,0.0004378136,0.00002636418,0.000005126094,0.00007338756,0.00000693267,0.00004166887,0.9986327,0.00009816155,0.00002625731,0.0005325903],"study_design_scores_gemma":[0.00001884331,0.0001459057,0.01673554,0.000006461433,0.00002135825,0.0004277484,0.00003868528,0.001038648,0.9781476,0.0001299172,0.003283702,0.000005649214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989476,0.00534926,0.002584347,0.0002965059,0.00005388991,0.00001623317,0.0003988112,0.00008219346,0.001742838],"genre_scores_gemma":[0.9946131,0.001303532,0.000601928,0.00005416205,0.00001563459,0.00001325142,0.000388937,0.00001847479,0.002991144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00201098,"threshold_uncertainty_score":0.006727397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02702565437534424,"score_gpt":0.2849050355329519,"score_spread":0.2578793811576076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}