{"id":"W2057006745","doi":"10.1007/s12253-013-9728-8","title":"Hypoxia-Inducible Factor-1α and its Role in the Proliferation of Retinoblastoma Cells","year":2013,"lang":"en","type":"article","venue":"Pathology & Oncology Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McGill University; McGill University Health Centre","funders":"","keywords":"Gene knockdown; Retinoblastoma; Transfection; Downregulation and upregulation; Western blot; Cell growth; Cancer research; Molecular biology; Biology; Chemistry; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001539426,0.0001318776,0.0002616426,0.0001694543,0.0001152204,0.00001759988,0.000321571,0.0004332922,0.00006996149],"category_scores_gemma":[0.0003052372,0.0001018721,0.00004709185,0.0002163061,0.0003479471,0.0000104942,0.0002075712,0.000457501,0.00004617168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002221876,"about_ca_system_score_gemma":0.0002565873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006094866,"about_ca_topic_score_gemma":0.0001882948,"domain_scores_codex":[0.9974442,0.001121259,0.0002871624,0.0004447756,0.0002108526,0.000491778],"domain_scores_gemma":[0.9990174,0.0001483795,0.00008116341,0.0003757201,0.0003009729,0.00007643479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008540263,0.0001399504,0.002086781,0.00001762961,0.00001170654,0.000006199944,0.0008425399,0.000003550092,0.9845023,0.0001635392,0.002093128,0.0100473],"study_design_scores_gemma":[0.001440311,0.002069653,0.08942597,0.00001169618,0.00001425263,0.0002004835,0.001426678,0.0000994603,0.8300006,0.0006909411,0.0744154,0.0002045892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913133,0.003556707,0.00001234101,0.0009824658,0.000246532,0.0007723423,0.00001401305,0.000005329419,0.003096987],"genre_scores_gemma":[0.996942,0.001263583,0.0001497077,0.0002602135,0.0004745553,0.0003202509,0.00001840518,0.00001563278,0.0005556622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1545017,"threshold_uncertainty_score":0.4154223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0391186215858364,"score_gpt":0.3468972717833421,"score_spread":0.3077786501975057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}