{"id":"W2057006745","doi":"10.1007/s12253-013-9728-8","title":"Hypoxia-Inducible Factor-1α and its Role in the Proliferation of Retinoblastoma Cells","year":2013,"lang":"en","type":"article","venue":"Pathology & Oncology Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McGill University; McGill University Health Centre","funders":"","keywords":"Gene knockdown; Retinoblastoma; Transfection; Downregulation and upregulation; Western blot; Cell growth; Cancer research; Molecular biology; Biology; Chemistry; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001843731,0.0001847891,0.0001626627,0.0004686493,0.0003533802,0.0003679351,0.0002567356,0.0002365432,0.001358431],"category_scores_gemma":[0.0001556288,0.0001501419,0.0001610114,0.0002795023,0.0003301304,0.0003004152,0.0001286494,0.0003766528,0.0003137379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006887085,"about_ca_system_score_gemma":0.0004017356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00391052,"about_ca_topic_score_gemma":0.002907029,"domain_scores_codex":[0.9999119,0.00001821989,0.000004404078,0.000009448965,0.00002305293,0.00003305381],"domain_scores_gemma":[0.9999183,0.00001192925,0.00002465592,0.000007872491,0.00001349043,0.00002370705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002363906,0.0001355448,0.004126097,0.0001614763,0.00002748885,0.0007177873,0.0001808908,0.0004798508,0.9766579,0.003155356,0.0005521319,0.01144166],"study_design_scores_gemma":[0.000095196,0.0007539667,0.0877941,0.00003745526,0.00005735753,0.002148138,0.0004878676,0.001972085,0.8832685,0.001528962,0.02183345,0.00002297731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9550219,0.03309738,0.002083277,0.001093595,0.00006903987,0.0000278699,0.0005524296,0.0000732543,0.007981244],"genre_scores_gemma":[0.9868224,0.006294181,0.0004931267,0.00005541888,0.00003671824,0.00001466979,0.000329949,0.000006506532,0.005946982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00391052,"threshold_uncertainty_score":0.007775486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0391186215858364,"score_gpt":0.3468972717833421,"score_spread":0.3077786501975057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}