{"id":"W2057012241","doi":"10.1016/j.biopsych.2013.12.018","title":"The Human Ortholog of Acid-Sensing Ion Channel Gene ASIC1a Is Associated With Panic Disorder and Amygdala Structure and Function","year":2014,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of Mental Health; U.S. Public Health Service; National Institutes of Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Amygdala; Panic disorder; Acid-sensing ion channel; Ion channel; Panic; Neuroscience; Function (biology); Gene; Psychology; Biology; Cell biology; Psychiatry; Genetics; Anxiety; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001234685,0.0001222723,0.0001219153,0.00001421309,0.0002012293,0.00001129936,0.00004579946,0.0002345668,0.00000366216],"category_scores_gemma":[0.00001521403,0.00006928251,0.00003450711,0.00005162817,0.0001738327,0.000002706501,0.00002126491,0.00007436605,1.435899e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002330582,"about_ca_system_score_gemma":0.00000843993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003952741,"about_ca_topic_score_gemma":0.00008940893,"domain_scores_codex":[0.9993513,0.0000581979,0.0001428326,0.0002465901,0.00006337078,0.0001377317],"domain_scores_gemma":[0.9996735,0.000007523704,0.0001110025,0.0001262963,0.00004717208,0.00003450704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003389588,0.00005927511,0.2736813,0.00001944715,0.0001214802,3.015479e-7,0.0000508628,0.00001339328,0.7189086,0.0007899979,0.0001246218,0.005891828],"study_design_scores_gemma":[0.000825722,0.001133436,0.9777086,0.00001688519,0.00004068554,0.000009842764,0.00009979788,0.00007670449,0.01580828,0.003310298,0.000789258,0.0001805141],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970396,0.0009901864,0.001395412,0.0002513145,0.0001632067,0.0001018427,0.00001330114,0.00001070468,0.00003445001],"genre_scores_gemma":[0.9992309,0.0001195032,0.00008429048,0.0001538886,0.0001668121,0.000001618832,0.000195357,0.000008468488,0.00003919658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7040274,"threshold_uncertainty_score":0.2825259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007730113400002649,"score_gpt":0.2090611275600892,"score_spread":0.2013310141600865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}