{"id":"W2057014824","doi":"10.1016/j.brainres.2007.11.063","title":"Beneficial effect of dipyridyl, a liposoluble iron chelator against focal cerebral ischemia: In vivo and in vitro evidence of protection of cerebral endothelial cells","year":2008,"lang":"en","type":"article","venue":"Brain Research","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"","keywords":"Neuroprotection; In vivo; Ischemia; Pharmacology; Blood–brain barrier; Superoxide dismutase; Chemistry; Brain damage; In vitro; Superoxide; Intracellular; Heme oxygenase; Brain ischemia; Oxidative stress; Medicine; Biochemistry; Heme; Central nervous system; Biology; Internal medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364586,0.0001464962,0.0003342132,0.0002081978,0.00003627245,0.000005455951,0.0001990074,0.0002685359,0.00001030875],"category_scores_gemma":[0.000611589,0.0001387962,0.00009021132,0.0003119338,0.0003166686,0.00001247752,0.0001931366,0.0003142418,8.393712e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000371894,"about_ca_system_score_gemma":0.0002204763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006602645,"about_ca_topic_score_gemma":0.0002089945,"domain_scores_codex":[0.998024,0.0004071184,0.0004080752,0.0003775789,0.000397985,0.000385184],"domain_scores_gemma":[0.9992819,0.0001549855,0.00009644751,0.0002871689,0.00009687502,0.00008258353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002651109,0.0001111208,0.005562497,0.0004106333,0.00001197722,0.000008198492,0.0001404736,0.00004408605,0.9899415,0.000003796644,0.0001223899,0.0009922261],"study_design_scores_gemma":[0.001529692,0.001071408,0.002134998,0.0001348947,0.000003015528,0.000005860206,0.0000452218,0.0003651475,0.9944991,0.000006158536,0.00009553922,0.0001089766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984307,0.0005454139,0.00001501897,0.00008180899,0.00003280701,0.0006318949,0.00003381601,0.000003149314,0.0002253969],"genre_scores_gemma":[0.9994112,0.0001422718,0.0001062503,0.00001192684,0.00009782906,0.00006608954,0.000006610526,0.000020009,0.0001377667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004557596,"threshold_uncertainty_score":0.5659944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02752206863631982,"score_gpt":0.3027823478869109,"score_spread":0.2752602792505911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}