{"id":"W2057062662","doi":"10.1002/ange.200705435","title":"A New Generation of Specific <i>Trypanosoma cruzi trans</i>‐Sialidase Inhibitors","year":2008,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Trypanosoma cruzi; Chemistry; Stereochemistry; Computational biology; Biology; Computer science; World Wide Web","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001898792,0.0005993104,0.0004277038,0.0002682405,0.0001671576,0.0003733567,0.0004707849,0.0004858576,0.001912676],"category_scores_gemma":[0.000133773,0.0002194293,0.0003507598,0.0002098319,0.0001772988,0.0003439375,0.0002720096,0.0009474642,0.0008127494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003480368,"about_ca_system_score_gemma":0.0002563318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004655,"about_ca_topic_score_gemma":0.0009449021,"domain_scores_codex":[0.999889,0.00001632987,0.000008303686,0.00002849792,0.00003452905,0.00002319681],"domain_scores_gemma":[0.9999431,0.000007846018,0.00001243216,0.000007875676,0.00001116504,0.00001755837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002018315,0.00008388983,0.0001236697,0.0001561742,0.00002011972,0.00008738741,0.00003190655,0.000151939,0.9794416,0.000700603,0.0007569685,0.01824384],"study_design_scores_gemma":[0.0001147864,0.001232819,0.0006947679,0.00002063984,0.00006225018,0.0007785122,0.00001202398,0.0004827063,0.9596375,0.000140246,0.03680393,0.00001978402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8305839,0.07236622,0.05794531,0.001682956,0.0007608063,0.0004428658,0.003252085,0.001162176,0.03180378],"genre_scores_gemma":[0.9008265,0.03315194,0.03201774,0.001058586,0.0001234005,0.0004995285,0.004748506,0.0001109685,0.02746283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001912676,"threshold_uncertainty_score":0.006398559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07073222470415848,"score_gpt":0.2913861463426783,"score_spread":0.2206539216385198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}