{"id":"W2057183626","doi":"10.1139/y2012-023","title":"The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Nursing Research; National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health","keywords":"Endocrinology; Internal medicine; Hypomagnesemia; Glutathione; Oxidative stress; Medicine; Tyrosine-kinase inhibitor; Tyrosine kinase; Biology; Chemistry; Receptor; Cancer; Magnesium","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008446955,0.0003169124,0.0003255153,0.0001475306,0.00006281152,0.0001204473,0.0001604779,0.0002395596,0.0006067476],"category_scores_gemma":[0.00006313719,0.0001065928,0.0001966981,0.00008158636,0.0001554514,0.0001310642,0.00009394976,0.0003776071,0.000145372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002003731,"about_ca_system_score_gemma":0.0001420503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003006748,"about_ca_topic_score_gemma":0.0005509177,"domain_scores_codex":[0.9999297,0.00001099821,0.000005922044,0.00001353464,0.00001947784,0.00002042093],"domain_scores_gemma":[0.9999294,0.000006603354,0.00003562166,0.000005376128,0.000005990313,0.00001704132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000374294,0.00006887077,0.000537747,0.00003267708,0.00001130925,0.00009153597,0.000005323832,0.00004708283,0.9969786,0.00003753492,0.00004705622,0.001767999],"study_design_scores_gemma":[0.0001466593,0.003963719,0.0203533,0.000009064413,0.0000699372,0.0009453351,0.00003215416,0.00139964,0.9711543,0.00006508465,0.001855095,0.000005759829],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976731,0.00101741,0.0006307592,0.00007031271,0.0000168004,0.00001672295,0.0001021139,0.00004553231,0.0004273516],"genre_scores_gemma":[0.9971048,0.0009390539,0.0005821651,0.00006230754,0.00001178806,0.00003106659,0.0002799357,0.000007178503,0.0009817156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006067476,"threshold_uncertainty_score":0.002029777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009710304864813744,"score_gpt":0.2526514131425379,"score_spread":0.2429411082777241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}