{"id":"W2057222672","doi":"10.1038/sj.ki.5002467","title":"Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity","year":2007,"lang":"en","type":"article","venue":"Kidney International","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; University of Victoria; National Institute of Diabetes and Digestive and Kidney Diseases; Cancer Research Institute; American Heart Association; National Institutes of Health","keywords":"Nephrotoxicity; Metallothionein; Proteinuria; Kidney; Biomarker; Urine; Creatinine; Medicine; Internal medicine; Chemistry; Endocrinology; Cadmium; Pathology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005994856,0.000154489,0.0001468156,0.00008843657,0.00005805872,0.00002600846,0.0004639504,0.0001157706,0.009685651],"category_scores_gemma":[0.0003086032,0.0001472757,0.0001048761,0.0002151906,0.0001935812,0.000406918,0.0001757093,0.0001415841,0.0004686081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001229033,"about_ca_system_score_gemma":0.00005691233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009651616,"about_ca_topic_score_gemma":0.00002810279,"domain_scores_codex":[0.9982737,0.00004672579,0.0003988982,0.0003291947,0.0006691106,0.0002824106],"domain_scores_gemma":[0.9988548,0.00002228044,0.000136266,0.0002799052,0.0000360033,0.0006707435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001692303,0.0004147461,0.1835191,0.000007059991,0.00008147371,0.00001641312,0.0004932725,0.000002067134,0.7395757,0.0004348943,0.07166731,0.00361873],"study_design_scores_gemma":[0.000423664,0.0001629901,0.3796299,0.00001630756,0.00001369462,0.000009018243,0.0000149958,0.0003315549,0.4872218,0.0005030234,0.1314307,0.0002423506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.932533,0.000001950596,0.003173779,0.001621156,0.0005112628,0.000164876,0.0002772478,0.00003824669,0.06167849],"genre_scores_gemma":[0.9863657,0.000002493417,0.002719706,0.009087227,0.0001089687,0.000006259594,0.00005088916,0.00001601918,0.001642725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2523538,"threshold_uncertainty_score":0.9912196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01705458801811627,"score_gpt":0.2848153567521444,"score_spread":0.2677607687340281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}