{"id":"W2057264887","doi":"10.1016/j.ab.2005.11.042","title":"Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay","year":2005,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Intracellular; DNA fragmentation; Caspase; Caspase 3; Enzyme; Apoptosis; Biochemistry; Molecular biology; Enzyme assay; Biology; Chemistry; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002794829,0.0001905274,0.0001730182,0.00004438702,0.0001029272,0.00002211578,0.0001087815,0.0002458583,0.00009615135],"category_scores_gemma":[0.00005266336,0.0001464378,0.00009870128,0.0001768139,0.0001472038,0.0000148305,0.00005613839,0.0002243965,0.000002826319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007866172,"about_ca_system_score_gemma":0.000116218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006522437,"about_ca_topic_score_gemma":0.00003705488,"domain_scores_codex":[0.9987377,0.00007211421,0.0003333086,0.0003687149,0.0002409408,0.0002472209],"domain_scores_gemma":[0.9992477,0.0000484854,0.0001731338,0.0003365072,0.0001063468,0.00008781047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002042265,0.0002080056,0.0001707483,0.00002090836,0.00005510374,0.000004381698,0.00003039826,0.01154476,0.9860768,0.00004190622,0.00003926269,0.001603463],"study_design_scores_gemma":[0.0005925185,0.0001265253,0.0009194725,0.00005905554,0.00007120226,0.00003164564,0.0003331098,0.06805444,0.9294266,0.00002693403,0.0001537154,0.0002048602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943982,0.0001359685,0.004636131,0.0001338499,0.00003984315,0.0001493996,0.00002005819,0.000007843489,0.0004787104],"genre_scores_gemma":[0.9980093,0.00003342642,0.00115145,0.00007888483,0.0002105813,0.000007035268,0.0002499069,0.00002133613,0.0002380265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05665031,"threshold_uncertainty_score":0.5971562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208835690476144,"score_gpt":0.2477659003788321,"score_spread":0.2356775434740706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}