{"id":"W2057277982","doi":"10.1080/15287390306450","title":"Physiological Modeling of Age-Specific Changes in the Pharmacokinetics of Organic Chemicals in Children","year":2003,"lang":"en","type":"article","venue":"Journal of Toxicology and Environmental Health","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Physiologically based pharmacokinetic modelling; Pharmacokinetics; Furan; Physiology; Inhalation; Blood flow; Age groups; Chemistry; Medicine; Pharmacology; Environmental chemistry; Internal medicine; Anesthesia; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004697068,0.00007421656,0.0002238643,0.00004198058,0.00001842694,0.000001396052,0.00009443299,0.00008620131,0.00002307268],"category_scores_gemma":[0.000008352777,0.00005387096,0.00004084812,0.00004157613,0.00009564906,0.000001941446,0.00003306463,0.0001501111,8.99101e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002631796,"about_ca_system_score_gemma":0.00002425464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003139873,"about_ca_topic_score_gemma":0.00002014947,"domain_scores_codex":[0.9991884,0.0001622244,0.0003302107,0.0001004811,0.00008230399,0.0001363699],"domain_scores_gemma":[0.9996818,0.00001331268,0.0001851184,0.0000791994,0.000003958671,0.000036597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005927856,0.0003706875,0.02979374,0.00001325387,0.00001638236,0.000003112866,0.0001602085,0.0006769425,0.9683658,0.00001317673,0.0000419777,0.0004854404],"study_design_scores_gemma":[0.003883779,0.004720856,0.4194749,0.00005563952,0.00002933532,0.0005140017,0.001928266,0.0002910164,0.5678367,0.0003468542,0.0006732701,0.0002453585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963941,0.003157476,0.00008380736,0.0002006736,0.0000244829,0.0001179921,0.000007959336,2.223467e-7,0.00001327401],"genre_scores_gemma":[0.9903634,0.009028977,0.0002226252,0.0003346843,0.0000342712,0.000001679302,0.00000792395,0.00000410555,0.000002403603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4005291,"threshold_uncertainty_score":0.2196794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02084205507266928,"score_gpt":0.2776246720080918,"score_spread":0.2567826169354225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}