{"id":"W2057278943","doi":"10.1111/j.1348-0421.2002.tb02688.x","title":"A Novel Genetic Algorithm for Designing Mimetic Peptides That Interfere with the Function of a Target Molecule","year":2002,"lang":"en","type":"article","venue":"Microbiology and Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Reverse transcriptase; Biology; Peptide; Computational biology; Human immunodeficiency virus (HIV); Domain (mathematical analysis); Algorithm; Bioinformatics; Genetics; Computer science; Biochemistry; RNA; Gene; Virology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005930012,0.0006914703,0.0006570932,0.0006553452,0.0003526989,0.0004851637,0.000805578,0.0009303369,0.001248542],"category_scores_gemma":[0.000949797,0.0003751592,0.000458333,0.0004747749,0.0005256197,0.000422495,0.0004071601,0.0005713285,0.0002391442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005961995,"about_ca_system_score_gemma":0.00090573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002645359,"about_ca_topic_score_gemma":0.00248072,"domain_scores_codex":[0.9997754,0.0000660433,0.00001270903,0.00004509306,0.00007397332,0.00002672516],"domain_scores_gemma":[0.9998171,0.0001014745,0.00001695396,0.00001068532,0.00004206703,0.00001181294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001270699,0.0001799538,0.001416795,0.0001315885,0.0001091935,0.000120949,0.00009632142,0.7552574,0.01856422,0.01342318,0.001731929,0.2088413],"study_design_scores_gemma":[0.00006956154,0.000103142,0.0001427695,0.000010329,0.00002141021,0.00005249313,0.00001059935,0.9923975,0.002403985,0.002702563,0.002074926,0.00001068539],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02764199,0.0002227408,0.9688785,0.0001199723,0.00004748991,0.0001319481,0.0000390141,0.0005162989,0.002401986],"genre_scores_gemma":[0.1326093,0.0001983291,0.8644214,0.000187725,0.0000307421,0.0004860448,0.0001270412,0.0000692367,0.001870152],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002645359,"threshold_uncertainty_score":0.005259931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644474010391805,"score_gpt":0.2105024766896326,"score_spread":0.1940577365857145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}