{"id":"W2057299439","doi":"10.1016/j.mcn.2010.05.007","title":"Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Neuroprotection; Neuroscience; Cytokine; Cell biology; Pharmacology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717525,0.0001633126,0.0001638356,0.00008630578,0.00005946636,0.00001756412,0.0001445086,0.0001443731,0.000006090728],"category_scores_gemma":[0.0001247002,0.0001613576,0.00006544353,0.0001881173,0.0002294338,0.000008699865,0.0001633887,0.0002404671,8.853951e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003357176,"about_ca_system_score_gemma":0.00004527826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005235642,"about_ca_topic_score_gemma":0.00003320731,"domain_scores_codex":[0.9988371,0.00007800188,0.0001632894,0.0005489471,0.0001179583,0.0002546765],"domain_scores_gemma":[0.9994602,0.000009311725,0.00009027021,0.0003066362,0.00005661467,0.00007693737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006272771,0.00006354006,0.0006318199,0.00001036976,0.00000185822,0.00002713652,0.0000422899,0.000005410491,0.9978244,0.0001158529,0.000003401301,0.0012112],"study_design_scores_gemma":[0.0004012418,0.0004263606,0.002916513,0.000005940068,0.000004621255,0.0000304348,0.00002110052,0.0002798185,0.9952729,0.00007717965,0.0004077822,0.0001561228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966626,0.00005682385,0.002590518,0.0001132791,0.0001521873,0.0001978167,0.00001445629,0.000007475491,0.0002048813],"genre_scores_gemma":[0.9993899,0.00001647623,0.0000776348,0.0004308647,0.00003224478,0.00001357395,0.000005411049,0.00001394992,0.00001989065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002727391,"threshold_uncertainty_score":0.6579973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009594210121368267,"score_gpt":0.2276173010857886,"score_spread":0.2180230909644203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}