{"id":"W2057306220","doi":"10.1007/s11302-006-9037-8","title":"Activation of transcription factors by extracellular nucleotides in immune and related cell types","year":2007,"lang":"en","type":"article","venue":"Purinergic Signalling","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Arthritis Network; Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research; Arthritis Society","keywords":"NFAT; Transcription factor; Cell biology; Immune system; CREB; Biology; Nucleotide; Extracellular; Receptor; Transcription (linguistics); Signal transduction; Cell signaling; Immune receptor; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003320627,0.0001417113,0.0001572364,0.00009212943,0.00003766568,0.000009164971,0.00008225419,0.0001446588,0.00004424418],"category_scores_gemma":[0.00002238898,0.0001384738,0.00005630317,0.0001387035,0.00004044992,0.00001098407,0.00002037392,0.0001082443,7.84117e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001006377,"about_ca_system_score_gemma":0.00001344098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008583607,"about_ca_topic_score_gemma":0.000001896635,"domain_scores_codex":[0.9990511,0.00003114412,0.000376081,0.0002343641,0.000108554,0.0001987878],"domain_scores_gemma":[0.999653,0.00003402034,0.000125786,0.0001013614,0.00003902105,0.00004685816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007153038,0.00006591425,0.005265723,0.00003576004,0.00001877522,0.000002983821,0.0001787828,0.00158947,0.9924256,0.00006149225,0.00006716699,0.0002168628],"study_design_scores_gemma":[0.0005489728,0.0001059316,0.00238039,0.00003856255,0.00001526519,0.000003003328,0.0002350271,0.0002756328,0.995429,0.0001026122,0.0007070309,0.0001585869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828896,0.01262738,0.003676292,0.00002061426,0.00004641776,0.0001025605,0.000002650431,0.00001082833,0.0006236728],"genre_scores_gemma":[0.9988204,0.0003228938,0.0002218452,0.000008965761,0.00004098533,0.000002065238,0.0000986707,0.0000213667,0.0004627566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01593086,"threshold_uncertainty_score":0.5646797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00689602144174972,"score_gpt":0.2093488281500054,"score_spread":0.2024528067082557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}