{"id":"W2057317496","doi":"10.1016/j.ydbio.2006.09.010","title":"Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility","year":2006,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research; Health Canada; Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"Epididymis; Efferent ducts; Biology; Vas deferens; Rete testis; Efferent; Hyperplasia; Immunohistochemistry; Epithelium; Endocrinology; In situ hybridization; Internal medicine; Andrology; Anatomy; Gene expression; Sperm; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003129948,0.0005003814,0.0004140632,0.000768621,0.0003590074,0.0007802002,0.0005790654,0.0005746747,0.003778067],"category_scores_gemma":[0.000284563,0.0006243727,0.0004912621,0.0003797956,0.0009362391,0.0004181429,0.0005233807,0.001270545,0.001043798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007002195,"about_ca_system_score_gemma":0.000535646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054896,"about_ca_topic_score_gemma":0.001919701,"domain_scores_codex":[0.9994833,0.00008015891,0.00006968074,0.0001054741,0.0001328516,0.0001284993],"domain_scores_gemma":[0.9993485,0.0001431155,0.0001423642,0.0001113479,0.00002715677,0.0002275256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000938421,0.00001905095,0.0001070011,0.000021282,0.000003915626,0.00008034652,0.00001099713,0.0000671547,0.9988862,0.0002618146,0.00001993779,0.0004285512],"study_design_scores_gemma":[0.00001379829,0.0000713625,0.001266462,0.000003179445,0.0000104214,0.0003243797,0.00002331557,0.0005074125,0.9968998,0.0000464161,0.0008295728,0.000003827568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894315,0.001624305,0.004287358,0.0002234414,0.00007439183,0.0000426991,0.001125936,0.0001928343,0.002997616],"genre_scores_gemma":[0.9845276,0.0006838734,0.002528919,0.00007365392,0.0000175259,0.00003297628,0.0009164792,0.00009087797,0.01112805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003778067,"threshold_uncertainty_score":0.01263893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008788580719863158,"score_gpt":0.2354724951396456,"score_spread":0.2266839144197824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}