{"id":"W2057321164","doi":"10.1038/sj.ki.5002691","title":"Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes","year":2007,"lang":"en","type":"article","venue":"Kidney International","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":188,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Fonds de Recherche du Québec - Santé; Kidney Foundation of Canada","keywords":"Podocyte; Phosphoinositide 3-kinase; Nephrin; Cell biology; Actin; Kinase; PI3K/AKT/mTOR pathway; Biology; Signal transduction; Endocrinology; Kidney; Proteinuria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000274734,0.0002590273,0.0002067134,0.0002990159,0.0004544701,0.000532749,0.0003299013,0.0004016075,0.001514335],"category_scores_gemma":[0.0001715686,0.0002578417,0.0002997023,0.0001412867,0.0002253031,0.0005959325,0.000503606,0.0006743142,0.0003839536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007119166,"about_ca_system_score_gemma":0.0002659953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009842644,"about_ca_topic_score_gemma":0.001845342,"domain_scores_codex":[0.9998053,0.00003340876,0.000011115,0.00002825127,0.00004608207,0.00007582563],"domain_scores_gemma":[0.9998931,0.00001491982,0.00002195244,0.00001462851,0.00001597749,0.00003950384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003861707,0.00003199516,0.0004060976,0.00005530687,0.00001012928,0.000185003,0.00003447598,0.00006197651,0.9964814,0.0006740491,0.0001172461,0.001556065],"study_design_scores_gemma":[0.00006388801,0.0001321332,0.03038925,0.0000104312,0.00002774212,0.0003971983,0.00009145236,0.002076691,0.9638794,0.0003572663,0.002566291,0.000008304512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900631,0.002383809,0.003234162,0.0003072859,0.00004979089,0.00003510719,0.0001535853,0.00006464864,0.003708463],"genre_scores_gemma":[0.9949915,0.000654168,0.00108512,0.0000600422,0.00001390767,0.00002580721,0.0001726189,0.000009057801,0.002987849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001514335,"threshold_uncertainty_score":0.005165339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006670785349556564,"score_gpt":0.2664394182947313,"score_spread":0.2597686329451748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}