{"id":"W2057345375","doi":"10.1016/s0009-9120(00)00054-0","title":"Evaluation of the accuracy of enzymatically determined carrier status for Krabbe disease by DNA-based testing","year":2000,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children; Janeway Children's Health and Rehabilitation Centre; Health Sciences Centre; Memorial University of Newfoundland","funders":"","keywords":"Krabbe disease; DNA; Computational biology; Chemistry; Disease; Biology; Medicine; Biochemistry; Internal medicine; Leukodystrophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.001496779,0.0001189126,0.0003071313,0.00001258584,0.00004658656,0.000007163613,0.0002056582,0.0001383668,0.0005083541],"category_scores_gemma":[0.05802468,0.00008486357,0.0002515762,0.0001963337,0.0003822703,0.00002256126,0.00003606976,0.0001786512,0.000002861049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007059495,"about_ca_system_score_gemma":0.001608611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001044278,"about_ca_topic_score_gemma":6.404189e-7,"domain_scores_codex":[0.9976667,0.0001505804,0.0007264434,0.0002935595,0.0009087517,0.0002539851],"domain_scores_gemma":[0.9957999,0.002129131,0.00021248,0.0006131835,0.0009500144,0.0002952937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002966845,0.002504352,0.2427441,0.002243355,0.0002271671,0.000005075714,0.00005480494,0.00006765936,0.419297,0.000002240133,0.005988535,0.3238989],"study_design_scores_gemma":[0.01343901,0.0006614754,0.1013379,0.0008299347,0.001442838,0.000002641445,0.00007824386,0.05386976,0.8264459,0.0004314032,0.001141328,0.0003195766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971658,0.0003920168,0.00003266449,0.0005454475,0.00003026688,0.0008025395,0.0002502032,0.00001372871,0.0007673499],"genre_scores_gemma":[0.9987138,0.000007734667,0.0005408605,0.0002008702,0.000069684,0.00007209396,0.00008456314,0.00001743602,0.0002929928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4071489,"threshold_uncertainty_score":0.94991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005370086547096,"score_gpt":0.4282193888933343,"score_spread":0.3276823802386247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}