{"id":"W2057348326","doi":"10.1016/j.taap.2013.12.010","title":"Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase","year":2013,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children’s Health Research Institute; McMaster University; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Offspring; Endocrinology; Internal medicine; Nicotine; Lactation; Fatty acid synthase; Biology; Pregnancy; Triglyceride; Steatosis; Medicine; Cholesterol; Lipid metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183004,0.0003125985,0.0002748967,0.0003969417,0.0001809154,0.0002881926,0.0002434667,0.0003240217,0.002062249],"category_scores_gemma":[0.0001684141,0.0003441653,0.0002823244,0.0001379569,0.000454502,0.0002177104,0.0002688004,0.0007766414,0.0003004121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003537118,"about_ca_system_score_gemma":0.0002873079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001678998,"about_ca_topic_score_gemma":0.003778496,"domain_scores_codex":[0.9998088,0.00001925432,0.00001269898,0.00005737105,0.00005753312,0.00004423717],"domain_scores_gemma":[0.9997206,0.00002913762,0.0000982164,0.00003279712,0.00002556092,0.00009365048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008063574,0.00007059237,0.002003413,0.00001555812,0.00001035776,0.0001645133,0.00005166367,0.00001861416,0.9946865,0.0001018859,0.00004432513,0.002026334],"study_design_scores_gemma":[0.00004169478,0.0008953906,0.1304278,0.00001841077,0.0001062624,0.001044035,0.0003469504,0.000594296,0.8648916,0.0002049825,0.001408436,0.00002010065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970365,0.0005651227,0.001265507,0.0001174269,0.00003781213,0.000007050435,0.0002511373,0.00004325816,0.0006763456],"genre_scores_gemma":[0.9905086,0.0007242109,0.001072068,0.00008338602,0.00001519321,0.00003463198,0.000340629,0.00004044755,0.007180877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002062249,"threshold_uncertainty_score":0.00689894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01445452772695107,"score_gpt":0.2870932028424346,"score_spread":0.2726386751154835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}