{"id":"W2057362221","doi":"10.1054/ceca.2001.0243","title":"Bcl-2 increases emptying of endoplasmic reticulum Ca2+ stores during photodynamic therapy-induced apoptosis","year":2001,"lang":"en","type":"article","venue":"Cell Calcium","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; QLT (Canada); University of British Columbia","funders":"","keywords":"Endoplasmic reticulum; Photodynamic therapy; Ionomycin; Apoptosis; Cell biology; HeLa; Mitochondrion; Chemistry; Intracellular; Biology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004723033,0.0004213541,0.000791188,0.0004708736,0.0004957892,0.0007103149,0.000418406,0.0007185805,0.002180503],"category_scores_gemma":[0.0008004069,0.0002705351,0.0003885746,0.000549837,0.0005618339,0.001067567,0.0003985011,0.001496037,0.0003379683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007596547,"about_ca_system_score_gemma":0.000425579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008236407,"about_ca_topic_score_gemma":0.001193501,"domain_scores_codex":[0.9996428,0.00007847572,0.00003129417,0.00003355812,0.0000746996,0.0001390067],"domain_scores_gemma":[0.9995425,0.000180546,0.00006998389,0.00007798382,0.00004629669,0.00008273018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005224094,0.0003190952,0.0004818652,0.0001129022,0.00002549142,0.0002901249,0.00009969498,0.0001283286,0.9881433,0.0004395692,0.00027358,0.004461906],"study_design_scores_gemma":[0.0002607316,0.001025173,0.004099345,0.00001047249,0.00004338674,0.0004834978,0.00009740043,0.001341311,0.990845,0.0001878397,0.001592864,0.00001306299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918663,0.003440019,0.001821861,0.0003450997,0.0001551656,0.00003440006,0.000177817,0.0002062957,0.001953066],"genre_scores_gemma":[0.9966382,0.0006725065,0.0006733298,0.00006259725,0.00003985253,0.00004078135,0.0001906162,0.00002161933,0.001660523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002180503,"threshold_uncertainty_score":0.007294536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01283761940540744,"score_gpt":0.2373404315907391,"score_spread":0.2245028121853317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}