{"id":"W2057390343","doi":"10.1159/000334103","title":"Bmi-1 Promotes the Chemoresistance, Invasion and Tumorigenesis of Pancreatic Cancer Cells","year":2011,"lang":"en","type":"article","venue":"Chemotherapy","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Pancreatic cancer; Gene knockdown; Carcinogenesis; Cancer research; Cancer; Gemcitabine; Gentamicin protection assay; Cancer cell; Biology; Epithelial–mesenchymal transition; PI3K/AKT/mTOR pathway; MTT assay; Small hairpin RNA; Cell growth; Medicine; Internal medicine; Cell culture; Metastasis; Signal transduction; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001197879,0.0002525137,0.0001679068,0.0002705785,0.0001494955,0.000247744,0.000116973,0.0001820829,0.002165964],"category_scores_gemma":[0.0001141578,0.0001217826,0.0001906242,0.000181212,0.0001742332,0.0001692207,0.000243857,0.000818835,0.0005165184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002615152,"about_ca_system_score_gemma":0.0002327181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006088107,"about_ca_topic_score_gemma":0.0008607846,"domain_scores_codex":[0.9999248,0.00001240641,0.000005962625,0.000009025896,0.00002832609,0.00001950665],"domain_scores_gemma":[0.9999186,0.00001404306,0.00002171413,0.000008440122,0.00001046748,0.0000267801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001724671,0.00005295887,0.0007568546,0.00006627149,0.000006266334,0.00006133776,0.00002166411,0.00008998502,0.9947981,0.0001288836,0.0002222695,0.00362304],"study_design_scores_gemma":[0.00005733998,0.0005187456,0.01904527,0.00001951535,0.00003247569,0.0005600438,0.00005724295,0.001918915,0.9684345,0.0001234645,0.009225055,0.000007374345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893305,0.004154208,0.002736242,0.0002592632,0.00004079462,0.00004081104,0.0003339626,0.0001599087,0.002944402],"genre_scores_gemma":[0.9936784,0.001775213,0.001402889,0.00005444585,0.00001061584,0.00003702411,0.0005954339,0.0000156613,0.002430225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002165964,"threshold_uncertainty_score":0.007245898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03290512694742647,"score_gpt":0.2583033382931245,"score_spread":0.225398211345698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}