{"id":"W2057494314","doi":"10.1158/1535-7163.targ-11-a19","title":"Abstract A19: Establishment of patient primary tumor-derived xenograft models for testing anticancer agents.","year":2011,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Micropharma (Canada)","funders":"","keywords":"Medicine; Irinotecan; Gemcitabine; Docetaxel; In vivo; Paclitaxel; Cancer; Cisplatin; Doxorubicin; Erlotinib; Cancer research; Primary tumor; Pharmacology; Colorectal cancer; Chemotherapy; Internal medicine; Metastasis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001421942,0.001075046,0.0007194295,0.0008049787,0.0004211219,0.0005232507,0.0006494196,0.0005372321,0.009990217],"category_scores_gemma":[0.0003142866,0.0003323504,0.0008450855,0.0008814592,0.0003216266,0.0004088177,0.0003849748,0.001334838,0.004246532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004732147,"about_ca_system_score_gemma":0.0007168972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084081,"about_ca_topic_score_gemma":0.001708726,"domain_scores_codex":[0.9991954,0.0001483367,0.000121327,0.0001912818,0.0002163543,0.0001273263],"domain_scores_gemma":[0.9994181,0.0001216835,0.00006951359,0.0001561491,0.0001142889,0.0001203135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001944528,0.001625899,0.003325895,0.0005167528,0.0001016267,0.0006780198,0.0001059551,0.0004323,0.9728808,0.000651215,0.005478367,0.01225869],"study_design_scores_gemma":[0.0003111636,0.007192578,0.01976481,0.00005029819,0.0002233441,0.005043487,0.00007167697,0.001614035,0.926692,0.0001461677,0.03885711,0.00003324121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8696562,0.009294414,0.04108942,0.0007102486,0.0007136183,0.004088284,0.04921177,0.001406143,0.02382996],"genre_scores_gemma":[0.8295777,0.00743357,0.04774356,0.0003957999,0.0001497682,0.002712406,0.08612075,0.0002819002,0.02558462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009990217,"threshold_uncertainty_score":0.03342062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06952482561264713,"score_gpt":0.3080648751406081,"score_spread":0.238540049527961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}